Mid luteal (day 20) serum progesterone concentration before and after; treatment arm 2.46 (±0.70) to 9.69 (±6.34), p < 0.001. Placebo 1.99 (±0.65) to 2.34 (±0.59) p = 0.08. No description of the distribution of drop-outs or missing data. This suggests the potential imbalance between intervention and control and a possible over-exaggeration for treatment effect.
Bajar de peso. Los hábitos de alimentación saludable y la actividad física en forma periódica pueden contribuir a aliviar los síntomas relacionados con SOP. Bajar de peso puede ayudar a reducir los niveles de glucosa en sangre, mejorar la forma en la que el cuerpo utiliza la insulina y ayudar a que las hormonas alcancen niveles normales. Inclusive un 10 % de pérdida de peso (por ejemplo, una mujer que pesa 150 libras y que baje 15) puede ayudar a que el ciclo menstrual sea más regular y que tengas más posibilidades de quedar embarazada. 3 Obtén más información sobre el peso saludable.
This review has some limitations. We used a methodological approach which was deductive and not consistent with traditional rationale for herbal selection. Our inclusion criteria for clinical studies were specific and relied upon our identification of herbal medicines with preclinical (laboratory based) evidence explaining the mechanisms of reproductive endocrinological effects in oligo/amenorrhoea, hyperandrogenism and PCOS. Clinical studies were excluded from this review due to the absence of evidence for whole herbal extracts. This was the case for Camellia sinensis (green tea) for which only one laboratory study investigated the effects of injecting epigallocatechin, a catechin found in green tea in animals [76]. High quality clinical evidence for Camellia sinensis was not presented in this review due to the absence of pre-clinical data explaining the mechanism for effect for the whole herbal extract [77]. Mentha spicata (spearmint) was another herbal medicine excluded from this review despite the availability of high quality clinical evidence demonstrating testosterone lowering effects in women with PCOS [78]. We found no laboratory evidence describing the mechanism of action for Mentha spicata in hyperandrogenism. Camilla sinensis and Mentha spicata are examples of herbal medicines excluded from this review due to not meeting the inclusion criteria. Studies investigating western herbal medicines excluded from this review are provided in Tables 3, ​,44 and ​and55.

Ang oral contraceptive pills (magkasamang estrogen at progestin) ay binibigay para maging regular ang regla ng babaeng may PCOS. Kapag nagreregla buwan buwan ang babaeng may PCOS ay hindi kumakapal ang lining ng matres at nakakatulong maiwasan ang kanser sa lining ng matres (endometrial cancer). Ang pag-inom ng contraceptive pills ay makakatulong din sa taghiyawat at sobrang buhok (bigote o sa dibdib at ibang parte ng katawan). Hindi rin mabubuntis habang umiinom ng pills.

Serum (blood) levels of androgens (hormones associated with male development), including androstenedione and testosterone may be elevated.[17] Dehydroepiandrosterone sulfate levels above 700–800 µg/dL are highly suggestive of adrenal dysfunction because DHEA-S is made exclusively by the adrenal glands.[61][62] The free testosterone level is thought to be the best measure,[62][63] with ~60% of PCOS patients demonstrating supranormal levels.[20] The Free androgen index (FAI) of the ratio of testosterone to sex hormone-binding globulin (SHBG) is high[17][62] and is meant to be a predictor of free testosterone, but is a poor parameter for this and is no better than testosterone alone as a marker for PCOS,[64] possibly because FAI is correlated with the degree of obesity.[65]


Clinical investigations found no adverse effects for the six herbal medicines included in this review (Table 2). A comparative study investigating the pharmaceutical Bromocriptine and the herbal medicine Vitex agnus-castus found no side effects associated Vitex agnus-ca stus compared to 12.5% of participants taking Bromocriptine reporting nausea and vomiting [63]. No studies comparing the effectiveness for herbal medicines and the oral contraceptive pill in PCOS, oligo/amenorrhoea and hyperandrogenism were found.
High cholesterol and triglyceride levels increase the risk of cardiovascular disease. Getting your cholesterol and triglyceride levels in an optimal range will help protect your heart and blood vessels. Cholesterol management may include lifestyle interventions (diet and exercise) as well as medications to get your total cholesterol, LDL, HDL, and triglycerides in an optimal range.
The goal of further evaluation of suspected PCOS is twofold: to exclude other treatable conditions that can mimic PCOS and to detect and treat long-term metabolic complications. Anovulation is common after menarche, so it is reasonable to delay workup for PCOS in adolescents until they have been oligomenorrheic for at least two years.28 If an adolescent is evaluated for PCOS, it has been suggested that she meet all three of the Rotterdam criteria before being diagnosed with the condition28  (Table 119).
Ask your health care provider about a weight loss plan if you are overweight. If you’re overweight, losing weight may lessen some of the symptoms of PCOS. Talk to your health care provider or nutritionist about healthy ways to lose weight such as exercising more and following a nutrition plan that helps manage insulin levels. Healthy eating can also keep your heart healthy and lower your risk of developing diabetes.
If these standard treatments don’t work, your doctor may recommend in vitro fertilization (IVF). Your egg is fertilized by your partner’s sperm in a lab, then transferred to your uterus to implant and grow. Your doctor may also recommend a surgical procedure called ovarian “drilling”. Lasers, or a very thin, heated needle, are used to pierce several holes in the surface of your ovary, which improves the chances of successful ovulation for about six to eight months. This is specifically effective for women with PCOS since the outer surface of the ovaries can become extra thick, interfering with the natural process of ovulation.
Fertilización in vitro (FIV). La FIV puede ser una opción en caso de que los medicamentos no funcionen. En una FIV, se fecunda tu óvulo con el esperma de tu pareja en un laboratorio y luego se lo implanta en tu útero para que se desarrolle. En comparación con los medicamentos, la FIV tiene mayores tasas de embarazo y mejor control sobre tu riesgo de tener mellizos y trillizos (al permitir que tu médico transfiera un solo óvulo fertilizado en el útero).

“It’s a frustrating, difficult, and sometimes heartbreaking thing to deal with,” Eaton said. Eaton’s PCOS has given her male-pattern baldness, acne, obesity, and skin tags. In spite of her challenging symptoms, she dances and works out several times a week. “There aren't many women who look like me who can get on the floor and move like I do, who are comfortable enough in their skin to step into the spotlight and demand that people look at them,” she said.
I was diagnosed with pcos while using implanon birth control in November 2012. I was told it was che...mical, it was symptom and blood diagnosed not with cysts on my ovaries. My ob/gyn told me that implanon can cause pcos and many other terrible medical conditions. I had it removed in January 2013 and have been trying to get pregnant since, after being told I needed a hysterectomy. (I was 24). In the past year I have gotten pregnant twice, both ended with miscarriage. In January this year, I had my blood tested again and I am almost completely normal. I'll always have pcos, it's life long, but the fact that after a year of getting the implanon removed I was able to get my blood back to normal. My endocrinologist called it miraculous!
hi dok? my concern din po ako irep. ang menstruation 6mos.hindi ako dinatnan then ngpahilot po ako kc ang alam namin ng husband ko buntis ako sbi nman ng manghihilot buntis ako, then after how many day ngbleed ako ngpacheck up ako tpos sbi nung ngpacheck upan ko hndi ako buntis. then ngayon ngmemens na rn po ako bwan bwan kso pabgo bgo ng mga dates and days ang mens ko. posible po bng my PCOS dn ako?

This is a great place for any event: there is a restaurant area for lunches and dinners, small tables for romantic evenings, a lounge area equipped with comfortable sofas and low tables, as well as a huge bar and a dance floor. AQUA LUNA’s summer terrace offers a splendid view onto the yacht club, the spires and roofs of the medieval Old Town, Vanšu Bridge, and modern business buildings – it is the ideal place to enjoy sunshine during the day, sunsets in evenings, and moonlight. In colder weather, AQUA LUNA warms hearts with its cosy atmosphere during long dinners by the fireplace and cheerful weekend parties.


More powerful and expensive imaging methods such as computed tomography (CT scan) and magnetic resonance imaging (MRI) can also detect cysts, but they are generally reserved for situations in which other conditions that may cause related symptoms, such as ovarian or adrenal gland tumors are suspected. CT scans require X-rays and sometimes injected dyes, which can be associated with some degree of complications in certain patients.
A long-term study suggested that metformin continued to improve the metabolic profile of women with PCOS over a 36-month treatment course, particularly improving circulating high-density lipoprotein cholesterol (HDL-C), diastolic blood pressure, and body mass index (BMI). [61] However, data are insufficient as yet to recommend metformin to all women with PCOS.
Chromium is an essential mineral that helps the body regulate insulin and blood sugar levels. Some research suggests that chromium supplements can help people with diabetes lower their blood glucose levels. One study examined the role of the mineral in women with PCOS. The results indicated that 200 mcg daily of chromium picolinate significantly reduced fasting blood sugar and insulin levels in subjects — enough that the effects were comparable to the pharmaceutical, metformin. While metformin was also associated with lower levels of testosterone, taking a daily dose of 200 mcg of chromium picolinate could help regulate blood sugar levels.
i understand that it's kind of the name of the game on this website but it just gets repetitive and boring after a while hearing people say the same things over and over again about her looks when 1) she really couldn't change it unless she had a ton of money (but we all know that'd just go to drugs) 2) like >>403879 and >>403866 said, she knows she's unattractive so there's no point in pointing out her bad physical qualities when everyone, including herself, gets it. and 3) most of the things that are being pointed out and mocked are normal and a lot of the people who post on this thread probably have the same things (like stretch marks. even if you aren't fat you can get those lol)
the last time luna deleted her blog, before she remade the one she has now, i googled her name because i couldn't find her blog and i wanted to see if she had another one, her lolcow page was like the 3rd result and i read every single thread within a few days. so, lolcow may only be the first google results to people who use lolcow BECAUSE they use lolcow, but for me, someone who had never even heard of the site before, it was still one of the first results. people who google her name never visiting lolcow before will still see these threads.
Janis King graduated cum laude from Florida State University in 2009 with a Bachelor of Science in Nursing and worked as a registered nurse in medical-surgical nursing and critical care. She earned her Doctor of Nursing Practice from Florida State University in 2013 and has since been working in Endocrinology following graduation.  Janis is bilingual and fluent in the Spanish language as well.
Fertilización in vitro (FIV). La FIV puede ser una opción en caso de que los medicamentos no funcionen. En una FIV, se fecunda tu óvulo con el esperma de tu pareja en un laboratorio y luego se lo implanta en tu útero para que se desarrolle. En comparación con los medicamentos, la FIV tiene mayores tasas de embarazo y mejor control sobre tu riesgo de tener mellizos y trillizos (al permitir que tu médico transfiera un solo óvulo fertilizado en el útero).
About Blog Natural treatment for better hormones and better periods. With this blog, I strive to assemble some truths, and to dispel some myths. I always want to better understand what works for hormones, and why, so I strive to keep abreast of current research, and my main motivation is always to help the patient sitting across from me. Blog by Lara Briden.
Doc ask k lng po sa inyo kng pwede ako inom ng metformin my pecos po ako.regular nman po regla ko.every month po meron kaya lng masakit ulo ko at puson pg ngkaroon ako.tpos may abdomenal pain po akng nramdamn lagi.ang binigay n gamot ng doctor ay ang purple corn juice po.pero d k po ito ininom pgkat mahal.mx3 capsule at tea lng po ang ininom ko mga 1 month na.pero masakit parin tiyan ko.tumataba dn ako doc.dahil wala npo ako excercise at trabaho.dalaga pa po ako.pls doc help me ano po ba dapat kng inumin para mawala ito.n stressed n po ako d2 lagi po sumasakit.
One note: “It takes about six months before the effect of these medications are seen on hair growth,” says David A. Ehrmann, MD, director of the University of Chicago Center for PCOS in Illinois. (This is because one hair growth cycle takes two to three months.) “When patients don’t know that, they get frustrated when they don’t see results quickly,” he says. Talk to your doctor about what you can realistically expect and when.
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
She is mentally ill and on tons of drugs all day long? Focusing on something shallow is doable in that kind of state. Plus she gets asspats for being cyberbullied by a mean forum lol. If she genuinely confronted the fact that she completely and utterly fucked up her life, that everything is her fault and she really just sucks as a person inside and out, she'd probably have a massive breakdown. She just numbs all of these feelings with drugs.
No one is quite sure what causes PCOS, and it is likely to be the result of a number of both genetic (inherited) as well as environmental factors. Women with PCOS often have a mother or sister with the condition, and researchers are examining the role that genetics or gene mutations might play in its development. The ovaries of women with PCOS frequently contain a number of small cysts, hence the name poly=many cystic ovarian syndrome. A similar number of cysts may occur in women without PCOS. Therefore, the cysts themselves do not seem to be the cause of the problem.
Shahin [68] Non-blinded randomised controlled trial. Women with PCOS and infertility, n = 194. All participants received pharmaceutical ovulation induction (Clomiphene citrate 150 mg on days 3–7 of cycle); trigger injection (HCG 10000 IU Pregnyl), timed intercourse and progesterone support (oral micronized progesterone). A randomly selected group additional took Cimicifuga racemosa 120 mg per day (Klimadynon®) Primary outcomes pregnancy rates. Secondary outcomes: Pregnancy rates were 33 out of 192 cycles (17.2%) for the clomiphene alone group and 71 out of 204 cycles (34.8%) for the clomiphene plus Cimicifuga racemosa group. Non-blinding compromised the internal validity of the findings in this study. Confounding variables include variations in participant’s and clinicians attitudes and may have led to differences which were unaccounted for between the two groups. However the outcomes are objective with a statistically powered sample size.
AQUA LUNA is just a few steps from the historical centre of Riga, in the quiet Andrejsala area. An old port where abandoned warehouses of imperial times are located next to a modern yacht-club, fashionable restaurants and night clubs, Andrejsala first became a popular leisure area for independent youth and bohemia, and more recently for high society and the wealthy. Industrial port buildings and the urban landscape add a special romanticism and piquancy to the area, which in the evenings becomes a centre of entertainment in Riga.

My brother was a Heroin addict who started taking Benzos between his shooting up, like Luna, versus the other way around. He was an addict, he took benzos to keep up whatever feeling he was chasing. Thats inherently different than an anxiety or depression patient taking them for relief of symptoms. Im sure it does happen, there's always that risk but I wouldn't go out there and say that Benzo use is always a gateway.

It's what's prescribed to me by a health care specialist aka my psychiatrist so I think I'm doing ok? It would be awful to get off of but I still exist like a regular person and sleep 8 hours a night thanks to seoquel. It did make me gain weight but I have that in control now. I can still do math problems and read books.. I just forget what I'm talking about sometimes


In addition to assessing signs and symptoms of PCOS, medical providers take a medical history, perform a physical exam, and check blood hormone levels (including testosterone). They may also perform an ovarian ultrasound. Other tests looking for complication of PCOS may also be done, such as glucose tolerance test or a mental health screening survey. 

Fertilización in vitro (FIV). La FIV puede ser una opción en caso de que los medicamentos no funcionen. En una FIV, se fecunda tu óvulo con el esperma de tu pareja en un laboratorio y luego se lo implanta en tu útero para que se desarrolle. En comparación con los medicamentos, la FIV tiene mayores tasas de embarazo y mejor control sobre tu riesgo de tener mellizos y trillizos (al permitir que tu médico transfiera un solo óvulo fertilizado en el útero).
If Chief goes to jail or gets probation, then she may have to. Or otherwise will eventually have to at some point. When addicts' junkie luck runs out and they begin to lose their basic comforts/necessities, they start to do things that they told themselves they'd never do. Nobody started out on heroin telling themselves that they'd do anything for the drug.
Weight loss achieved through dietary changes and exercise can help women with PCOS in several ways. Like men and women without PCOS, losing weight reduces a person's risk of cardiovascular disease and non-insulin dependent (type 2) diabetes. Weight loss also helps to lower the level of insulin in the body which, in turn, reduces the ovaries' production of testosterone.
Los ovarios de la mujer tienen folículos, que son los sacos diminutos y llenos de líquido que contienen los óvulos. Cuando el óvulo madura, el folículo lo libera para que pueda desplazarse al útero para la fertilización. En mujeres con el síndrome, los folículos inmaduros se agrupan y forman quistes o bultos grandes. Los óvulos maduran con los grupos de folículos, pero los folículos no se abren para liberarlos.

However, in women with PCOS receiving low doses of gonadotropins for timed intercourse, metformin administration can double the clinical pregnancy rate (OR 2.25; 95% CI: 1.50 to 3.38; p<0.001; 7 trials) and the live birth rate (OR 1.94; 95% CI: 1.10 to 3.44; p=0.020; 2 trials). Moreover, this practice can reduce the cancellation rate due to ovarian hyperresponsiveness by approximately 60% (OR 0.41; 95% CI: 0.24 to 0.72; p=0.002; 7 trials), the number of days of stimulation (mean difference (MD)=-3.28; 95% CI: -6.23 to 0.32; p=0.030; 6 trials) and the dose of gonadotropins (MD=-306.62; 95% CI: -500.02 to -113.22; p=0.002; 7 trials) in low-complexity cycles. However, the use of metformin is not related to a reduction in the multiple pregnancy rate (OR 0.32; 95% CI: 0.08 to 1.23; p=0.100; 3 trials), a change in the miscarriage rate (OR 0.47; 95% CI: 0.14 to 1.54; p=0.210; 5 trials) or OHSS (OR 0.56; 95% CI: 0.26 to 1.21; p=0.140; 5 trials). Notably, no conclusive data are available on the appropriate dose and time (pre-treatment or during gonadotropin treatment) for the use of metformin during timed intercourse with gonadotropins 37.
Yeah, PCOS isn't period-dependent. That said, there are some suspicious blood stains in Luna's apartment that look like leaks (though they could possibly be explained by shooting up). Though since she does have PCOS, painful periods are one of those things she actually has grounds to complain about. Apparently they're often excruciating beyond belief with the condition.
She is mentally ill and on tons of drugs all day long? Focusing on something shallow is doable in that kind of state. Plus she gets asspats for being cyberbullied by a mean forum lol. If she genuinely confronted the fact that she completely and utterly fucked up her life, that everything is her fault and she really just sucks as a person inside and out, she'd probably have a massive breakdown. She just numbs all of these feelings with drugs.
Ano nga ba ang PCOS? Ito ay isang hormonal disorder kung saan nagkakaroon ang babae ng mga maliliit na cyst sa kanyang obaryo. Naglalaman ang mga cyst na ito ng mga immature egg cells na hindi kayang mag-trigger ng proseso ng obulasyon. Ibig sabihin, bababa ang lebel ng female hormones tulad ng estrogen at progesterone, at tataas ang lebel ng male hormones katulad ng androgen. Ang imbalance na ito ay magdadala ng iba’t ibang sintomas at epekto sa katawan.
Getting three hours of exercise a week is enough to improve insulin sensitivity in women with PCOS, especially if you have been inactive up until now. Exercise can help you lose more weight, but more importantly, it can also help you lose the fat around your abdomen – that’s what contributes directly to insulin resistance, which fuels PCOS symptoms – even if you don’t lose any weight. That’s what happened in a 2017 small Monash University study.16  Women in this study added interval training (ie, short bursts of high-intensity exercise followed by regular or moderate intensity intervals) for part of their workout.16
Azziz R; Woods KS; Reyna R; Key TJ; Knochenhauer ES; Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004 Jun;89(6):2745-9. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004 Jan;81(1):19-25. 

Oldfag from up top. Just saying yes, thank you and agreed. On all my medical paperwork it says that I have benzodiazepine dependency. I am physically dependent but I also function–I can work, I can manage my life. The thing that upsets me is that these days, I would never have been given benzos as the first med for my illness, I would have been given something that's less physically addictive and potentially dangerous. In the long term I believe benzos aren't good for you at all, and I'm certainly long term.

Ya que el PCOS no se puede curar, es importante controlar la afección de su hija. Manténgase en contacto con el proveedor de atención médica de su hija, hablándole con sinceridad sobre la efectividad del tratamiento y la respuesta de la niña; menciónele si nota algún cambio nuevo. Y lleve a su hija a hacerse chequeos de control regulares para garantizar que le detecten y controlen cualquier problema de salud.
The prescription cream eflornithine HCl can slow the growth of new hair when applied as directed on the face and other areas – but it won’t remove existing hair. 20,21 Your doctor may also prescribe a medication called an anti-androgen. In the United States, a medication called spironolactone is used to slow new hair growth. In other countries, cyproterone acetate is widely used but it is not available in the United States.  
In vitro fertilization represents the third-line treatment for infertility in women with PCOS 9. However, if the initial assessment demonstrates a bilateral tubal occlusion and/or concentration of recovered motile sperm less than or equal to 5 million, this treatment becomes the first option along with lifestyle changes. The risk of OHSS is the main complication of the highly complexity treatment in women with PCOS. Thus, to minimize this side effect, ovarian stimulation should be initiated with low doses of gonadotropins (100 to 150 IU of FSHr) and the pituitary should be suppressed with a gonadotropin-releasing hormone (GnRH) antagonist because this method is associated with a reduced risk of OHSS compared with an agonist (29 randomized control trials (RCTs); OR 0.43; 95% CI: 0.33 to 0.57) 32. If the patient presents with clinical and ultrasound signs of OHSS, final oocyte maturation should be performed with a GnRH agonist and embryos should be frozen and transferred in a subsequent cycle 33,34. Infertile women with PCOS may present with better general oocyte and embryo quality rates; however, the clinical pregnancy and live birth rates are similar to those observed in normo-ovulatory women without PCOS 35.
Like >>409129 said, there are non-opioid painkillers. But the chemical component of opioids that relieves pain is not the same component that causes a high anyway. We already have partial opiate agonists (like Suboxone) that people have been on for years. From what I've read about a vaccine like this, opioids could still be administered with the intended effect of substantial pain relief. With no unwanted side effects (high). Someone please correct me if I'm wrong, this prospect really excites me. Something like this could lead to a whole new class of painkilling drugs for people with chronic pain, allowing them to function without being high at all times.
Saw Palmetto (Serenoa repens, Sabal serrulata) This herb has anti estrogenic effects and also has been found to decrease the testosterone levels in the blood. Both effects are very positive for women with PCOS .9 The herb has properties that can block the process of testosterone turning into DHT (dihydrotestosterone, a by-product of testosterone) which in turn lowers male hormones in the body.

Combination birth control pills — those with estrogen and Prometrium (progesterone) — are frequently prescribed to women with PCOS not looking to get pregnant. If the main concern is irregular periods and the resulting potential health risks, this is a great option. “Birth control pills are very good for protecting the lining of the uterus in women who are chronically anovulatory,” says Dunaif.
Lifestyle measures to achieve a weight loss of 5%-10% in overweight women can help regulate ovulation and periods. Although the basic approach of nutrition is needed, it can be more challenging to lose weight and maintain weight loss with PCOS. Dr. Dunaif from Northwestern is very encouraging that even “a little bit of weight reduction and exercise can improve insulin sensitivity.”
Si bien no se recomienda como primer tratamiento, existe una operación para el tratamiento de PCOS, llamada incisión ovárica. Se realiza un pequeño corte encima o debajo del ombligo y se inserta un pequeño instrumento llamado laparoscopio que sirve como telescopio en el abdomen. Durante la laparoscopía, el médico puede hacer punciones en el ovario con una aguja delgada que tiene corriente eléctrica para destruir una pequeña porción del ovario. La cirugía puede mejorar los niveles hormonales y la ovulación, aunque es posible que la mejoría dure solo unos meses.
Serum (blood) levels of androgens (hormones associated with male development), including androstenedione and testosterone may be elevated.[17] Dehydroepiandrosterone sulfate levels above 700–800 µg/dL are highly suggestive of adrenal dysfunction because DHEA-S is made exclusively by the adrenal glands.[61][62] The free testosterone level is thought to be the best measure,[62][63] with ~60% of PCOS patients demonstrating supranormal levels.[20] The Free androgen index (FAI) of the ratio of testosterone to sex hormone-binding globulin (SHBG) is high[17][62] and is meant to be a predictor of free testosterone, but is a poor parameter for this and is no better than testosterone alone as a marker for PCOS,[64] possibly because FAI is correlated with the degree of obesity.[65]
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