just saying, sometimes on payday i head to the drugstore and buy one or two nyx lip products along with other stuff and they're just under 10 euro a pop here. Like on payday I feel pretty dodgy for paying 30 euro for like three lip products. I imagine even her dad would feel weird about spending that much money on something so stupid when he could get her groceries or actual useful bathing products instead.
88. Moghetti P, Castello R, Negri C, Tosi F, Perrone F, Caputo M, Zanolin E, Muggeo M. Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation. J Clin Endocrinol Metab. 2000;85:139–146. [PubMed]
Hi doc..may katanungan lang po sana ako.last year na diagnosed po na may PCOS ako,pro bago po madiagnosed un,3 months po ako dinudugo(ireg po ang period ko simula ng nag trabaho ako sa call center) kaya kala ko ok lng po un dahil sanay naman po ako na ireg kaya pinabayaan ko po ung 3 months na pag dudugo.naalarma lang po ako at nagpatingin sa ob dahil ung pang 3rd moth ng pag durugo,sjmobra na po ang lakas na pakiramdam ko po ay mauubusan ako ng dugo sa lakas at geabe po ang buo buo.dun po mag decide ako magpatingin agad ako pina transvaginal ng doctor,dun po lumabas na my pcos ako,at bukod po doon,sobrang kapal na po mg lining ng matres ko at nsa result din po nakalagay na rinerefer na po ako sa endocrinologist.pero ang ginawa po ng ob ko is pinainom ako ng provera at ipinaliwanag ang pcos at ung tungkol sa kapal ng lining ng matresko.nabahala po ako dahil sabi po sa akin,kelngan daw po ako raspahin dahil sa kapal nito.pro neg refuse din po ung ob ko gwn ung procedure na un dhl daw po wla pa po akong amak at asawa.kya,provera at after ng provera,althea pills lng po ang iniinom ko.ang tanong ko lng po doc,posible po ba na normal na ang matres ko dahil 1 year mhgit ndn po mula ng ngng ok ang period ko dahil sa pills?kung hindi po,ano po ba ang maipapayo nyo na gawin ko doc?nag babasa basa po kc ako,high risk dw po sa endometrial cancer ang gmitong case.by d way po doc,26 years old po ako.salamat po at sna masagot nyo po ako.Godbless

I smoke indoors and as long as you keep the window open and vacuum slightly more often there's no noticeable grime. You should clean your walls with cold water once a year or so to stop build-up of random crap regardless of whether you smoke. Tuna's grime has built up over years of neglect, smoking probably hasn't helped but it's mainly because she's nasty.
While PCOS is not curable, symptoms are treatable with medications and changes in diet and exercise. Hormonal imbalances can be treated with birth control pills, androgen blocking medications, or medications that help the body use insulin better. Medications that help the body respond better to insulin may also be helpful. For women whose infertility problems are not resolved with lifestyle changes alone, medications that improve ovulation (fertility drugs) may be helpful.
The prevalence of depression in women with polycystic ovary syndrome (PCOS) is high; a study has shown it to be four times that of women without PCOS. Therefore, systematic evaluation of the effectiveness and safety of antidepressants for women with PCOS is important. We found no evidence to support the use or non‐use of antidepressants in women with PCOS, with or without depression. Well‐designed and well‐conducted randomised controlled trials with double blinding should be conducted.
The cysts (fluid filled sacs) in the ovaries can be identified with imaging technology. (However, as noted above, women without PCOS can have many cysts as well.) Ultrasound , which passes sound waves through the body to create a picture of the kidneys, is used most often to look for cysts in the ovaries. Ultrasound imaging employs no injected dyes or radiation and is safe for all patients including pregnant women. It can also detect cysts in the kidneys of a fetus. Because women without PCOS can have ovarian cysts , and because ovarian cysts are not part of the definition of PCOS, ultrasound is not routinely ordered to diagnose PCOS. The diagnosis is usually a clinical one based on the patient's history, physical examination, and laboratory testing.
Chicken and egg: was Luna an asshole who started drugs and became even more of an asshole, or did she start drugs that turned into an asshole? A lot of what's wrong with her has little to do with her addiction - e.g. her desperate attempts at focusing everything into a mad scramble for sympathy (some bum died, so she wrote a story that made it look as if he had been her closest friend so people tell her they're sorry etc.) derive from her being an asshole, not from her addiction. Anyone who consciously wants to become a junkie for an aesthetic is already way deeply fucked imho.
Women who do not wish to become pregnant can be effectively treated for hirsutism with oral contraceptives. [77] Oral contraceptives slow hair growth in 60-100% of women with hyperandrogenemia. Therapy can be started with a preparation that has a low dose of estrogen and a nonandrogenic progestin. Preparations that have norgestrel and levonorgestrel should be avoided because of their androgenic activity. There is also a risk of thrombotic events in obese women who use oral contraceptives; therefore, the proper precautions should be exercised to prevent such events. Oral contraceptives containing cyproterone acetate are also very effective in the treatment of more severe hirsutism [78] ; however, this combination of agents has not been approved by the FDA for use in the United States.
Women with PCOS have a normal uterus and healthy eggs. Many women with PCOS have trouble getting pregnant, but some women have no trouble at all. If you’re concerned about your fertility (ability to get pregnant) in the future, talk to your health care provider about all the new options available, including medications to lower your insulin levels or to help you ovulate each month.
Otros síntomas del PCOS son provocados por problemas con la insulina, otra hormona del cuerpo. La insulina ayuda a que el azúcar (también llamada glucosa) pase del torrente sanguíneo a las células para que la utilicen como energía. Cuando las células no responden normalmente a la insulina, aumenta el nivel de azúcar en la sangre. Además, el nivel de insulina sube a medida que el cuerpo produce más y más para tratar de que la glucosa llegue a las células. Demasiada insulina aumenta la producción de andrógenos,5 que luego causan los síntomas del PCOS. Los niveles altos de insulina también pueden aumentar el apetito y provocar un aumento de peso.3 Los niveles de insulina altos también se relacionan con la enfermedad llamada acantosis nigricans.3
PCOS son las siglas en inglés del síndrome de ovario poliquístico, una afección común en mujeres adolescentes y adultas. PCOS ocurre cuando hay un desequilibrio hormonal. Además de estrógeno (la principal hormona femenina), las mujeres también producen una pequeña cantidad de testosterona (la principal hormona masculina). Las muchachas y mujeres con PCOS producen un poco de testosterona adicional.
Treatment of polycystic ovary syndrome is individualized to treat prevailing signs/symptoms and generally focused on correcting irregular bleeding from the uterus, restoring fertility, improving the skin manifestations of androgen excess (hirsutism, acne, hair loss), and preventing diabetes and cardiovascular disease. More recently, attention has also focused on improving the quality of life in PCOS women who have body image concerns.
The definitive cause of PCOS is unknown, but researchers have found a strong link to insulin resistance, a genetic condition often associated with diabetes, in which the muscle, fat, and liver cells do not respond properly to insulin and thus cannot easily absorb glucose (sugar) from the bloodstream. As a result, the body produces higher and higher levels of insulin to help glucose enter the cells.
Moran, L. J., Ko, H., Misso, M., Marsh, K., Noakes, M., Talbot, M., … Teede, H. J. (2013, April). Dietary composition in the treatment of polycystic ovary syndrome: A systematic review to inform evidence-based guidelines [Abstract]. Journal of the Academy of Nutrition and Dietetics, 113(4), 520–545. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/23420000
If you’ve been told you have PCOS, you may feel frustrated or sad. You may also feel relieved that at last there is a reason and treatment for the problems you have been having, especially if you have had a hard time keeping a healthy weight, or you have excess body hair, acne, or irregular periods. Having a diagnosis without an easy cure can be difficult. However, it’s important for girls with PCOS to know they are not alone. Finding a health care provider who knows a lot about PCOS and is someone you feel comfortable talking to is very important. Keeping a positive attitude and working on a healthy lifestyle even when results seem to take a long time is very important, too! Many girls with PCOS tell us that talking with a counselor about their concerns can be very helpful. Other girls recommend online chats. The Center for Young Women’s Health offers a free and confidential monthly online chat for girls and young women with PCOS.
Limitations of direct insulin testing and cumbersome calculations have led to research for indirect serum markers to provide evidence of IR. SHBG correlations to IR as previously mentioned have been inconsistent. Adiponectin is a protein found in adipose tissue associated with both inflammation and insulin action. Recent studies have linked plasma adiponectin level to IR (but not hyperandrogenism) measured by HOMA[56-58]. Serum soluble glycoprotein-130 levels (local cytokine) have been inversely correlated to IR[59]. Resistin plasma levels have been correlated with fasting glucose and HOMA-IR in PCOS women[60]. Inhibin A levels in PCOS women were not found to correlate with IR in PCOS women[61]. Most of these serum markers share common limitations and have been poorly studied. How they might vary with different PCOS phenotypes is unknown. None are adequately compared to IR measured by clamp studies. Their usefulness serially in clinical practice to monitor patients over time and undergoing treatment is also unknown. Some genetic work has recently shown promise. Although far from clinical use, microarray analysis of genes in muscle, adipose tissue and the liver shows alterations in the setting of IR[62]. Serum genetic markers may lead to future genetic techniques to detect and monitor IR.
Another study, a double-blind trial by Legro et al, found that letrozole is more effective than clomiphene in the treatment of infertility in PCOS. Based on treatment periods of up to five cycles, the study, which involved 750 anovulatory women with PCOS, found that the birth rates for letrozole and clomiphene were 27.5% and 19.1%, respectively. The rate of congenital abnormalities and the risk of pregnancy loss in the letrozole and clomiphene groups were found to be comparable, although the likelihood of twin births was lower with letrozole. [53, 54]

34. Griesinger G, Schultz L, Bauer T, Broessner A, Frambach T, Kissler S. Ovarian hyperstimulation syndrome prevention by gonadotropin-releasing hormone agonist triggering of final oocyte maturation in a gonadotropin-releasing hormone antagonist protocol in combination with a "freeze-all" strategy: a prospective multicentric study. Fertil Steril. 2011;95(6):2029–33. http://dx.doi.org/10.1016/j.fertnstert.2011.01.163 [PubMed]


Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
Clinical equivalence for prolactin lowering effects of Vitex agnus-castus (Agnucaston® 40 mg per day) and the pharmaceutical Bromocriptine (Parlodel® 5 mg per day) was found in one study including 40 women with hyperprolactinaemia [63]. Mean concentrations for prolactin following three months treatment with Vitex agnus-castus was significantly reduced from 946 mIU/l (±173) to 529 mIU/l (±297) (p < 0.001). Comparatively, mean prolactin concentration in the Bromocriptine group was significantly reduced from 885 mIU/l (±178) to 473 mIU/l (±266) (p < 0.001) demonstrating that both treatments were effective treatment for women with hyperprolactinaemia (normal reference range 25-628 mIU/l). The mean difference in prolactin reduction of the two groups was not significant (p = 0.96) (Table 2).
Combination oral contraceptives, especially those with progestins of norgestimate, desogestrel, or drospirenone (because of their low androgenic effects), are among the most commonly used medications for hirsutism in women with PCOS.2 However, they are not approved by the U.S. Food and Drug Administration (FDA) for this use. One study found that women taking desogestrel/ethinyl estradiol (Apri) had lower hirsutism scores on a standardized scale (i.e., the Ferriman-Gallwey hirsutism score).34 Finasteride (Propecia) and flutamide (formerly Eulexin) are effective, but are FDA pregnancy categories X and D, respectively; the use of these agents for hirsutism is strictly off-label.2

This comprehensive 5-Element System will support your body’s ability to balance hormones by helping to improve your energy, lose weight, regulate your period and ovulation, balance moods, reverse and stop dark, coarse dark facial and body hair growth, stop thinning hair and regrow new beautiful hair, improve skin health and improve blood sugar balance, along with a myriad of hormonal symptoms including digestion.


Wang et al. 2008 [66] Double blinded, placebo controlled randomised trial (pilot). Eight weeks. 15 overweight women with oligo/amenorrhoea and polycystic ovaries on ultrasound. Mean body mass index 28.8 ± 1.3 kg/m2. Mean age 31.1 ± 2.0 years Cinnamomum cassia extract 333 mg (Integrity Nutraceuticals International Sarasota, Florida) or placebo. One tablet three times per day. Primary outcomes: Insulin resistance and sensitivity. Secondary outcomes oestradiol and testosterone concentration. Body mass index (BMI). Before and after treatment comparisons between randomised groups plus comparison between treatment group and normal ovulatory, normal weight women. Adverse events. Improved insulin sensitivity (QUICKI) in the treatment group. 0.35 to 0.38, (7.7%) p < 0.03. Insulin resistance (HOMO-IR) significantly reduced in treatment group 2.57 to 1.43 (44.5%) p < 0.03. Controls no change insulin sensitivity or insulin resistance. No change in either group for BMI, testosterone and oestradiol. Differences between Cinnamomum cassia group and normal weight and ovulatory controls were not significant. (P < 0.17). No reported adverse reactions. Small pilot study, the authors report that larger studies are required to confirm findings. Small sample size may explain non-significant comparison with normal weight and ovulating women. Reproductive outcomes were unchanged in this study however the duration of the study was insufficient to demonstrate reproductive changes.
Yeah, PCOS isn't period-dependent. That said, there are some suspicious blood stains in Luna's apartment that look like leaks (though they could possibly be explained by shooting up). Though since she does have PCOS, painful periods are one of those things she actually has grounds to complain about. Apparently they're often excruciating beyond belief with the condition.
Medicamentos antiandrógenos. Estos medicamentos bloquean el efecto de los andrógenos y ayudan a reducir la caída del cabello, el crecimiento del vello facial y corporal y el acné. No están aprobados por la Administración de Alimentos y Medicamentos (FDA, por sus siglas en inglés) para el tratamiento de los síntomas del SOP. Estos medicamentos también pueden generar problemas durante el embarazo.
Metformin(Glucophage) is a medication used to treat type 2 diabetes. This drug affects the action of insulin and is useful in reducing a number of the symptoms and complications of PCOS. Metformin has been shown to be useful in the management of irregular periods, ovulation induction, weight loss, as well as the prevention of type 2 diabetes and gestational diabetes mellitus in women with PCOS.
Women with PCOS have a normal uterus and healthy eggs. Many women with PCOS have trouble getting pregnant, but some women have no trouble at all. If you’re concerned about your fertility (ability to get pregnant) in the future, talk to your health care provider about all the new options available, including medications to lower your insulin levels or to help you ovulate each month.
Sylvia Rebecca - "I have to share how good I feel since joining this program. I have been on it for 3 weeks. I take the supplements faithfully, started working out, eat better and drink half my body weight in water. My mood swings are better and I just feel happier. For the last 3 years I have been depressed and did not want to do anything, but look at me now. I am hoping that my period will start soon. This is the next step for me. I do not get a period without taking Provera. You guys are also an amazing group of women and so happy to be on this journey with all of you. A NEW ME!!!!!!"
Pre-clinical and clinical evidence was found for Vitex agnus-castus for lowered prolactin, improved menstrual regularity and treatment of infertility. Vitex agnus-castus contains a variety of compounds which bind to dopamine type 2 (DA-2) receptors in the brain; reduce cyclic adenosine mono phosphate (cAMP) and lowered prolactin secretion (Table 1). This was demonstrated in studies using recombinant DA-2 receptor proteins, and basal and stimulated rat pituitary cell cultures [38–41]. Prolactin lowering effects were found in normal and ovariectomised rats [49]. Additional agonistic opiate effects were observed in studies using human opiate receptors cell cultures [70].
Fertility Treatments: Once other possible reasons for infertility in you and your partner have been ruled out, your gynecologist or fertility specialist may recommend the drug clomiphene (Clomid) to induce ovulation. Six months of treatment has been known to achieve successful pregnancies for about 20-40% of women with PCOS,19 according to ACOG. If clomiphene is tried and isn’t effective, you may be given gonadotrophins to try and jumpstart your ovaries.
Los complementos alimenticios no deben utilizarse como sustitutos de una dieta variada, equilibrada y de un estilo de vida saludable. No superar la dosis diaria recomendada. Si está  pensando en tomarlo consulte antes con su médico. Mantener fuera del alcance de los niños más pequeños. Conservar en un lugar fresco y seco, protegido de la luz solar y las fuentes de calor. Consumir preferentemente antes de la fecha indicada en el envase.
Nope, it was definitely her, I can't forget it. On tumblr sometime earlier last year she kept posting these depressed frantic posts about that sad disgusting old crackhead guy she loves so much and is like her only family. hes always so sick and slowly dying, she felt responsible for not being able to provide for or truly help him like he "helped" her (i suspect he just gives her drugs). there was a pic of the ambulance, her crying in the ER, and the huge bill and everything. she deleted everything within hours of posting, I guessed it was the embarrassment, but those went around in reblogs for a long time. She's always covered in a layer of filth and on her tumblr there was a pic of her doing drugs outside in the winter wearing a holey mini skirt with freshly open track marks on a swingset with a caption like "I can't even get high anymore but I'm scared withdrawal would kill me". It just made me wanna cry and I gave her the $5 even though I knew she would just use it for more drugs. Is that enabling?
Women who do not wish to become pregnant can be effectively treated for hirsutism with oral contraceptives. [77] Oral contraceptives slow hair growth in 60-100% of women with hyperandrogenemia. Therapy can be started with a preparation that has a low dose of estrogen and a nonandrogenic progestin. Preparations that have norgestrel and levonorgestrel should be avoided because of their androgenic activity. There is also a risk of thrombotic events in obese women who use oral contraceptives; therefore, the proper precautions should be exercised to prevent such events. Oral contraceptives containing cyproterone acetate are also very effective in the treatment of more severe hirsutism [78] ; however, this combination of agents has not been approved by the FDA for use in the United States.
Patients with PCOS who are infertile but desire pregnancy should be referred to a reproductive endocrinologist for further evaluation and management of infertility. Morbidly obese women with PCOS should also be referred for pregnancy risk [2] ; metabolic surgery may be considered in morbidly obese women with PCOS, because many features of this syndrome are reversible with successful weight loss. In vitro fertilization (IVF) is reserved for women with PCOS and unsuccessful gonadotropin therapy or those with other indications for this procedure. [2]
Nigga u wot?? Seriously, read through at least one of her threads before virtue signaling. She is NOT a "sweet woman." She talks shit about everyone once they stop giving her money or ass pats. She claims her dad is the absolute worst and yet brags when he buys her a new grandma bra or when they smoke weed together. She HAS been to rehab, but dropped it once she realized it wasn't a cool place to hang out with druggies.

Gymnema (Gymnema sylvestre) This is a common herb used in traditional Ayurvedic medicine and has been called the herbal form of Metformin.3 It is an anti-diabetic that is characterized by insulin modulating activity which means it regulates insulin levels while controlling sugar or carbohydrate cravings. Gymnema actually numbs the sweet taste areas of the taste buds which helps suppress appetite. Some research has indicated that this herb might stimulate production of cells in the pancreas which in turn increases the levels of insulin in the body.


Like >>409129 said, there are non-opioid painkillers. But the chemical component of opioids that relieves pain is not the same component that causes a high anyway. We already have partial opiate agonists (like Suboxone) that people have been on for years. From what I've read about a vaccine like this, opioids could still be administered with the intended effect of substantial pain relief. With no unwanted side effects (high). Someone please correct me if I'm wrong, this prospect really excites me. Something like this could lead to a whole new class of painkilling drugs for people with chronic pain, allowing them to function without being high at all times.


Jump up ^ Pundir, J; Psaroudakis, D; Savnur, P; Bhide, P; Sabatini, L; Teede, H; Coomarasamy, A; Thangaratinam, S (24 May 2017). "Inositol treatment of anovulation in women with polycystic ovary syndrome: a meta-analysis of randomised trials". BJOG : An International Journal of Obstetrics and Gynaecology. 125 (3): 299–308. doi:10.1111/1471-0528.14754. PMID 28544572.
Our search identified 33 laboratory (pre-clinical) studies (Figure 1). Eighteen studies met the inclusion criteria, nine reported on receptor binding assays or ovarian or pituitary (brain) cell cultures, [36–44] and nine used an animal experimental model with hormone assays and/or post-mortem examination of ovarian, uterine and brain histology, [45–53] (Table 1). We excluded 15 studies for the following reasons; investigation of effects in male animals (n = 4) and investigations which commenced with constituents that were isolated from herbal medicines (n = 5). Six studies were excluded due to no clinical evidence found (n = 6).
Es posible que el médico también te pida un análisis de sangre para diagnosticar un síndrome de ovario poliquístico u otras afecciones, como los problemas de la tiroides, de los ovarios o de otras glándulas. Los análisis de sangre permiten medir las concentraciones de andrógenos, insulina y otras hormonas. Los resultados de estas pruebas pueden ayudar a los médicos a determinar el tipo de tratamiento que debes recibir.
On March 1, 2012, the US Food and Drug Administration (FDA) updated health care professionals regarding changes to the prescribing information concerning interactions between protease inhibitors (drugs for management of human immunodeficiency virus [HIV] and hepatitis B infection) and certain statin drugs. The combination of these drugs may raise the blood levels of statins and increase the risk for myopathy. Rhabdomyolysis, the most serious form of myopathy, can cause kidney damage and lead to kidney failure, which is life threatening. [62]
PCOS is the most common endocrinopathy among reproductive-aged women in the United States, affecting approximately 7% of female patients.1 Although its exact etiology is unclear, PCOS is currently thought to emerge from a complex interaction of genetic and environmental traits. Evidence from one twin-family study indicates that there is a strong correlation between familial factors and the presence of PCOS.2
hi doc bru ! ask ko lng po 7 years na po kami nagsasama ng asawa ko nagpafertility check naman po kami 2 years ago . ok nman po sperm count nia at ok nman din po ung ultrasound ko may nakita lng po na maliliit na bukol sa uterus ko . niresetahan po ako ng metmorfin fertyl at folic acid. regular nman po 28 days ung cycle ko! pero until now ndi pa din po kami nakakabuo . ano po ba the best way na gawin namin para magkababy na? i hope po na masagot nio .. thankyou en godbless po
76. Chen J-T, Tominaga K, Sato Y, Anzai H, Matsuoka R. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Alternative Compl Med. 2010;16(12):1295–1299. doi: 10.1089/acm.2009.0696. [PubMed] [CrossRef]

Asimismo, muchas chicas con síndrome de ovario poliquístico se pueden quedar embarazadas. Si mantienes relaciones sexuales, necesitas utilizar preservativos en cada ocasión para no quedarte embarazada ni contraer ninguna enfermedad de transmisión sexual (ETS). Esto es muy importante, independientemente de que padezcas o no un síndrome de ovario poliquístico.
Just fyi, when a cat stops grooming itself, it's a sign that it's about to die. Or at least something is seriously wrong, physically or psychologically. Elderly cats typically stop grooming themselves when they're about to die. I'm a vet tech, and have seen cats in their early 20's that still groom themselves. They may need a bit of help with their back ends due to arthritis, but a well cared for cat of any age will at least try.
I reckon probably the latter though, people do actually want to help her, to the extent that people get pissed off as fuck if you express any of that sort of sentiment in here because we've heard it so often. I imagine a lot of posters view her like PT but worse - it's just frustrating to watch someone ruin their life so spectacularly and reject all the things that would actually make their life better.
No one is quite sure what causes PCOS, and it is likely to be the result of a number of both genetic (inherited) as well as environmental factors. Women with PCOS often have a mother or sister with the condition, and researchers are examining the role that genetics or gene mutations might play in its development. The ovaries of women with PCOS frequently contain a number of small cysts, hence the name poly=many cystic ovarian syndrome. A similar number of cysts may occur in women without PCOS. Therefore, the cysts themselves do not seem to be the cause of the problem.
Hi doc..may katanungan lang po sana ako.last year na diagnosed po na may PCOS ako,pro bago po madiagnosed un,3 months po ako dinudugo(ireg po ang period ko simula ng nag trabaho ako sa call center) kaya kala ko ok lng po un dahil sanay naman po ako na ireg kaya pinabayaan ko po ung 3 months na pag dudugo.naalarma lang po ako at nagpatingin sa ob dahil ung pang 3rd moth ng pag durugo,sjmobra na po ang lakas na pakiramdam ko po ay mauubusan ako ng dugo sa lakas at geabe po ang buo buo.dun po mag decide ako magpatingin agad ako pina transvaginal ng doctor,dun po lumabas na my pcos ako,at bukod po doon,sobrang kapal na po mg lining ng matres ko at nsa result din po nakalagay na rinerefer na po ako sa endocrinologist.pero ang ginawa po ng ob ko is pinainom ako ng provera at ipinaliwanag ang pcos at ung tungkol sa kapal ng lining ng matresko.nabahala po ako dahil sabi po sa akin,kelngan daw po ako raspahin dahil sa kapal nito.pro neg refuse din po ung ob ko gwn ung procedure na un dhl daw po wla pa po akong amak at asawa.kya,provera at after ng provera,althea pills lng po ang iniinom ko.ang tanong ko lng po doc,posible po ba na normal na ang matres ko dahil 1 year mhgit ndn po mula ng ngng ok ang period ko dahil sa pills?kung hindi po,ano po ba ang maipapayo nyo na gawin ko doc?nag babasa basa po kc ako,high risk dw po sa endometrial cancer ang gmitong case.by d way po doc,26 years old po ako.salamat po at sna masagot nyo po ako.Godbless
Three RCTs corroborate the positive fertility effects for Cimicifuga racemosa in women with PCOS, used in conjunction and when compared with the pharmaceutical Clomiphene citrate (clomiphene), [65, 68, 71] (Table 2). Results were reported for 441 women and show improved pregnancy rates when Cimicifuga racemosa was added to clomiphene during one menstrual cycle. In a study including women with PCOS (n = 147), pregnancy rates for the group receiving combined therapy (clomiphene 150 mg plus Cimicifuga racemosa 20 mg per day (Klimadynon®)) were 43.3% compared to 20.3% for women receiving only clomiphene [65] (Table 2). In another study using similar methodology (n = 100) pregnancy rates were 34.8% for the group treated with Cimicifuga racemosa plus clomiphene compared to 17.2% for women treated with clomiphene alone [68] (Table 2). Another study included women with PCOS and infertility (n = 100) compared Cimicifuga racemosa (Klimadynon®) and clomiphene over three months for hormone concentrations and pregnancy rates. Pregnancy rates were higher in the women in taking Cimicifuga racemosa compared to clomiphene, 14% and 8% respectively; however differences were not statistically significant. This study found significant effects for lowered luteinising hormone for women with PCOS receiving Cimicifuga racemosa compared to clomiphene (p = 0.007) [67]. Findings from clinical studies concur with laboratory and animal studies; however potential risks for bias include performance and collection bias due to lack of blinding (Table 2).
In vitro fertilization represents the third-line treatment for infertility in women with PCOS 9. However, if the initial assessment demonstrates a bilateral tubal occlusion and/or concentration of recovered motile sperm less than or equal to 5 million, this treatment becomes the first option along with lifestyle changes. The risk of OHSS is the main complication of the highly complexity treatment in women with PCOS. Thus, to minimize this side effect, ovarian stimulation should be initiated with low doses of gonadotropins (100 to 150 IU of FSHr) and the pituitary should be suppressed with a gonadotropin-releasing hormone (GnRH) antagonist because this method is associated with a reduced risk of OHSS compared with an agonist (29 randomized control trials (RCTs); OR 0.43; 95% CI: 0.33 to 0.57) 32. If the patient presents with clinical and ultrasound signs of OHSS, final oocyte maturation should be performed with a GnRH agonist and embryos should be frozen and transferred in a subsequent cycle 33,34. Infertile women with PCOS may present with better general oocyte and embryo quality rates; however, the clinical pregnancy and live birth rates are similar to those observed in normo-ovulatory women without PCOS 35.
The prescription cream eflornithine HCl can slow the growth of new hair when applied as directed on the face and other areas – but it won’t remove existing hair. 20,21 Your doctor may also prescribe a medication called an anti-androgen. In the United States, a medication called spironolactone is used to slow new hair growth. In other countries, cyproterone acetate is widely used but it is not available in the United States.  
Traditionally, women with polycystic ovary syndrome (PCOS) have been treated with therapies aimed at relieving specific PCOS symptoms or health risks. Newer treatments being investigated at the University of Chicago Medicine and elsewhere also aim to address what may be a root cause of PCOS: insulin resistance. Many of these new therapies are designed to lower insulin levels, thus reducing production of testosterone.
Ovarian drilling has some advantages compared with gonadotropin treatment because it is associated with a lower multiple gestation rate (OR 0.13; 95% CI: 0.03 to 0.52; p=0.004; I(2)=0%; 5 trials; n=166) 29 and does not require US monitoring of follicular development 9. However, the long-term impact of ovarian drilling on the ovarian reserve/ovarian function remains unknown 29.
Peer reviewers: Luciano Pirola, PhD, Epigenetics in Human Health and Disease Laboratory, Baker IDI Heart and Diabetes Institute, 5th floor, 75 Commercial Road, Melbourne VIC 3004 Australia; Marcin Baranowski, PhD, Department of Physiology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland; Christa Buechler, PhD, Department of Internal Medicine I, Regensburg University Hospital, Regensburg D93042, Germany
Be sure to check out theAsianparent Community for more insightful stories, questions, and answers from parents and experts alike. If you have any insights, questions or comments regarding the topic, please share them in our Comment box below. Like us on Facebook and follow us on Google+ to stay up-to-date on the latest from theAsianparent.com Philippines!
Our laboratory search included investigations into the effects of herbal medicine using computer models, cell cultures, animals with PCOS induced with oestradiol valerate and androgens and sterilised and ovariectomised rats. We excluded laboratory studies which commenced using isolated chemicals not directly extracted from crude herbal medicines and studies examining androgen effects in male animals.

Randomisation for 206 women 12 were excluded due to failure to respond (treatment group n = 7, control n = 5). 2. Endometrial thickness monitored by ultrasound. Endometrial thickness in the clomiphene alone group was 8.5 mm (±1.9) compared to 12.9 (±2.3) in the clomiphene plus Cimicifuga racemosa group (p < 0.001). The miscarriage rate per pregnancy for the clomiphene alone group was 5 out of 33 (15.2%) and 6 out of 71 (8.5%) in the clomiphene plus Cimicifuga racemosa group.


Weight loss achieved through dietary changes and exercise can help women with PCOS in several ways. Like men and women without PCOS, losing weight reduces a person's risk of cardiovascular disease and non-insulin dependent (type 2) diabetes. Weight loss also helps to lower the level of insulin in the body which, in turn, reduces the ovaries' production of testosterone.
Ask your health care provider about a weight loss plan if you are overweight. If you’re overweight, losing weight may lessen some of the symptoms of PCOS. Talk to your health care provider or nutritionist about healthy ways to lose weight such as exercising more and following a nutrition plan that helps manage insulin levels. Healthy eating can also keep your heart healthy and lower your risk of developing diabetes.
×