Oldfag from up top. Just saying yes, thank you and agreed. On all my medical paperwork it says that I have benzodiazepine dependency. I am physically dependent but I also function–I can work, I can manage my life. The thing that upsets me is that these days, I would never have been given benzos as the first med for my illness, I would have been given something that's less physically addictive and potentially dangerous. In the long term I believe benzos aren't good for you at all, and I'm certainly long term.
Disclosure: Eli Lilly & Co Grant/research funds Investigator; MacroGenics, Inc Grant/research funds Investigator; Ipsen, SA (formerly Tercica, Inc) Grant/research funds Investigator; NovoNordisk SA Grant/research funds Investigator; Diamyd Grant/research funds Investigator; Bristol-Myers-Squibb Grant/research funds Other; Amylin Other; Pfizer Grant/research funds Other; Takeda Grant/research funds Other

Preclinical and clinical studies provide evidence that six herbal medicines may have beneficial effects for women with oligo/amenorrhea, hyperandrogenism and PCOS. However the quantity of pre-clinical data was limited, and the quality of clinical evidence was variable. Further pre-clinical studies are needed to explain the effects of herbal medicines not included in this review with current clinical evidence but an absence of pre-clinical data.


i would suggest researching a bit online. but from my experience working in treatment centers yes, meth has foul chemicals. when they first come in and are detoxing from it addicts smell like chemical and ammonia. there are so many foul and unnatural things in it it reeks havoc on the human body. i know she mentioned crack but i don't think we have any real proof luna has ever used meth.


It's good to know I'm not alone with having pcos. I found out when I was 18 years old. When I was gr...owing up and in puberty I never had my period. I remember girls around me complaining about there's in high school. But mine never came. I went to a obgyn when I was 16 she gave me meds to get it started, it only worked when I took the med every 3 months. They also did an ultrasound and found multiple cysts on my ovaries, but she did not know what it was. So I never went back to that doctor she was not very bright. But when I was 18 I was reading a magazine about a girl that has pcos and the symptoms and everything, and it sounded like me. So i went to My mom's obgyn and talked to him about what I read and my history of not getting my period on my own, he did an exam, ran some blood tests, and did other ultrasound. Come to find out I have pcos and was put on birth control and metformin. Which I'm still taking and it's been 11 years since I found out I have pcos. See More
Many women with PCOS exhibit symptoms of insulin resistance and metabolic syndrome, risk factors that raise the risk for heart disease and other problems like diabetes and stroke. Low magnesium levels are often associated with diabetes, and some research indicates that a dietary supplement of the mineral may improve insulin sensitivity, a factor in the development of type 2 diabetes and PCOS. One study found that overweight, insulin-resistant subjects who received 300 mg of magnesium at bedtime showed a significant improvement in fasting blood glucose and insulin levels, compared to subjects who received a placebo.
I'm too stupid to work out how to scroll thru Tuna's previous likes on Tumblr, but that Draco Malfoy crap reeks of bullshit to me. She liked some autismo essay about "what it'd be like dating draco as a non-slytherin" yesterday, it sounds like she made this up after reading it. I've never heard her make a reference to ~Draco or Harry Potter before now, I guess she's trying to fit in with the nerd side of Tumblr.

Human speak: Polycystic ovarian syndrome (PCOS) is one of the most common female reproductive disorders; affecting approximately 10% or more of women worldwide. PCOS is a big deal because it can lead to infertility and other health problems. The common symptoms associated with PCOS are irregular or no periods and anovulation (meaning you don’t ovulate, or ovulate rarely), increases in androgen hormones (like testosterone) and luteinizing hormone (which usually kicks off ovulation, but is persistently high in women with PCOS), and in some cases, insulin resistance and obesity. There is currently no “cure” for PCOS, just management of symptoms.
Weight loss is also a key first step if you’re planning a pregnancy. It may improve your ability to get pregnant by restoring ovulation3 or make your body more responsive to fertility treatments if that is what is determined you need. In fact, up to 75 percent of women with PCOS who were able to reduce their body weight also had better glucose control and improved androgen hormone levels, helping to restore ovulation and fertility,2,3 experts say.  
The differential diagnosis of PCOS is broad and includes both endocrinologic and malignant etiologies. Figure 119 provides an algorithm for the workup of select presentations. For any woman with suspected PCOS, the Endocrine Society recommends excluding pregnancy, thyroid dysfunction, hyperprolactinemia, and nonclassical congenital adrenal hyperplasia.19 Depending on presentation, conditions such as hypothalamic amenorrhea and primary ovarian insufficiency should also be excluded. In women with rapid symptom onset or significant virilization, such as deepening voice or clitoromegaly, an androgen-secreting tumor should be ruled out. Finally, Cushing syndrome or acromegaly should be excluded in patients with physical findings that suggest either condition.19 There is no need to order laboratory testing for these conditions if the patient does not have suggestive physical findings.
I don't want to be a cow thank you. No, I'm not naturally ginger. My friend was on my account last night taking the piss. I've deleted the comments because I'm not a cunt who comments horrible things on people's profiles. We was talking about Luna because I found this thread. I don't even know what the comments meant myself, I was confused. So yeah, say what youse like I'm not really arsed.
Thanks for the clarification, I dont know anything about her or any of the side characters besides a few posts i've skimmed here and those tumblr posts from earlier 2016. I wouldn't be mean to any of them. I think they could really use some kindness. I just find a lack of hygiene to be repulsive due to my own personal germaphobia, i can't even expand and pics in the thread because my skin crawls and shudders and it makes me really nauseous just to see a stained shirt, its my problem. I'm sure she's just a sweet woman whose addiction has her spiraling downward with no way to get into a good rehab place. If they could get enough money for a facility program and keep a sober companion a few years, I think they could have a chance to get better and take care of Roger before he dies.

Polycystic ovary syndrome (PCOS) is a condition associated with hormone imbalances that affects women. Though the underlying cause of PCOS is not known or well understood, it is believed that an imbalance of sex hormones and resistance to the effects of the hormone insulin are the main problems. These problems result in a characteristic group of signs, symptoms and complications such as excess facial and body hair, irregular menstrual periods, infertility, and insulin resistance.


Although the exact cause of PCOS is not known, there are several factors that are associated with the condition. It is closely linked to high levels of hormones such as insulin and testosterone, but it is not clear if this is a cause or an effect of the condition. Additionally, it appears to run in some families, which suggests that there may be a genetic link in the pathogenesis of the condition.

Where US is available, CC treatment should be initiated between the third and fifth day of the menstrual cycle and the couple should abstain from intercourse (this is not a mandatory measure) until the tenth day of the cycle (when the presence of dominant follicles with a mean diameter of 10 mm or more is assessed via US). Sexual activity is allowed if the patient presents with monofollicular or bifollicular development. The goal of sexual abstinence until the tenth day of the cycle is to minimize the risk for multiple gestations.
The diagnostic workup should begin with a thorough history and physical examination. Clinicians should focus on the patient's menstrual history, any fluctuations in the patient's weight and their impact on PCOS symptoms, and cutaneous findings (e.g., terminal hair, acne, alopecia, acanthosis nigricans, skin tags).19 Patients should also be asked about factors related to common comorbidities of PCOS.
“When any condition crosses disciplines and doesn’t have a full investment in [one of them], it often falls through the cracks. There are elements of reproduction in PCOS, but most reproductive endocrinologists mostly do in-vitro fertilization and are not necessarily interested in metabolism. Medical endocrinologists, who are mostly interested in metabolism, aren’t usually interested in reproduction and ovarian function,” Dumesic said.
Many health experts believe that numerous variables, including genetics, might be a factor in the development of PCOS. For example, you might find your sister, mother, aunt or grandmother has PCOS. It is clear that hormone imbalance is a primary influencing factor in PCOS as well as a condition called insulin resistance. Insulin is a potent hormone which is released by the pancreas as a result of food intake, in particular carbs. Insulin conveys sugar out from the blood and moves it into other cells such as muscle, liver and even fat cells. The sugar is then changed into energy or in some cases stored as fat. Sometimes this process is defective which is called insulin resistance.
If he was using heroin very heavily, that may well be his starting methadone dose (or close to it.) Methadone has a long half life while heroin has a short one, so avoiding withdrawals can take a lot of methadone, initially. Methadone clinics aren't going to leave someone on a high dose though. They'll titrate up until withdrawal subsides, then taper down over time. I'm guessing he started at the clinic around when he got busted, so it's sus af to me that he'd still be taking 130mg. Or that he ever was. Maybe 100. Possibly.
I worded that badly. What I mean is that opiates themselves don't relieve pain, but alter the perception of pain. It's possible to alter that perception of pain in other ways, which is why substances like SSRIs cause significant pain relief for some people with some conditions. Ditto with anticonvulsants. Opioids aren't the only drugs that affect norepinephrine and mU receptors, they just happen to be the best at it. If the pleasurable effects of opioids were blocked, there's still therapeutic potential in the "inert" components, like THC vs. CBD.
Many women with PCOS have decreased sensitivity to insulin, the hormone that regulates glucose (sugar) in the blood. This condition, known as insulin resistance, is a major risk factor for type 2 diabetes. Women with PCOS often have type 2 diabetes, which occurs more frequently in women with PCOS. Signs of insulin resistance include weight gain (especially around the waist), acanthosis nigricans (skin thickening around the neck, armpits, belly, button, and other creases), and skin tags.
PCOS is due to a combination of genetic and environmental factors.[6][7][15] Risk factors include obesity, not enough physical exercise, and a family history of someone with the condition.[8] Diagnosis is based on two of the following three findings: no ovulation, high androgen levels, and ovarian cysts.[4] Cysts may be detectable by ultrasound.[9] Other conditions that produce similar symptoms include adrenal hyperplasia, hypothyroidism, and high blood levels of prolactin.[9]
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