Moran, L. J., Ko, H., Misso, M., Marsh, K., Noakes, M., Talbot, M., … Teede, H. J. (2013, April). Dietary composition in the treatment of polycystic ovary syndrome: A systematic review to inform evidence-based guidelines [Abstract]. Journal of the Academy of Nutrition and Dietetics, 113(4), 520–545. Retrieved from

La depresión o cambios anímicos también son comunes en mujeres con el síndrome. Si bien se requiere más investigación para averiguar sobre esta relación, hay muchos estudios que establecen una relación entre la depresión y la diabetes. Por lo tanto, con PCOS, es posible que la depresión esté relacionada a la resistencia de insulina. También puede ser resultado de desequilibrios hormonales y síntomas cosméticos del trastorno. El acné, la pérdida de cabello y otros síntomas de PCOS pueden disminuir la autoestima. La infertilidad y los abortos naturales también pueden ser estresantes. Los medicamentos que restablecen el equilibrio de los niveles hormonales o los antidepresivos pueden ayudar a sobrellevar estos sentimientos.
Bergmann J, Luft B, et al. [62] Randomised, placebo controlled double blind study. Three months or 3 menstrual cycles. Women with fertility disorders, (n = 67). Two sub-groups. Herbal extract Phyto-Hypophyson® by Steril-Pharma GmbH Herrsching, Germany; contains Vitex agnus-castus plus Chelledonium majus and Silybum marianum (St Mary’s thistle) in homeopathic form. Additional herbal extracts have reported activity in hepatic function. There are no reports for direct reproductive effects. 150 drops per day (7.5 ml per day). Primary outcome for participants with amenorrhoea: at least one spontaneous menses. Oligomenorrhoeic subgroup - clinical outcomes were significantly improved in the treatment arm at 82% compared to 45% in placebo arm P = 0.021. When the amenorrheic group were included in analysis, differences were not significant p = 0.19. Diagnosis for anovulatory amenorrhoea is not well described. Non-statistically significant take home baby rates were complicated by insufficient sample size. 366 patients are required to have a 95% chance, as significant at the 5% level, an increase in take home baby rates from 6% in the placebo group to 18% in the experimental group. The authors conclude that this preparation may be useful if given 3–6 months, yet they only tested for 3 months.
In PCOS, both ovaries tend to be enlarged, as much as three times their normal size. Eggs that do not mature fully are not released during ovulation and the immature eggs remain in the ovary as pearl-sized, fluid filled sacs. Over the course of time, many cysts may develop into what looks like a string of beads when viewed through ultrasound imaging. In as many as 90% of women with PCOS, an ultrasound of the ovaries will reveal cysts.
“Often times the cosmetic issues are huge, depending on the severity. When you summarize the typical PCOS patient as someone who is fat, has acne, and male-pattern baldness, that is definitely depressing, but that in and of itself is not enough to cause depression,” she said. “It’s the hormonal imbalances that have a real neurobiological affect on the brain and we have evidence that the excess of androgens in women is definitely linked to depression.”
Herbal medicine may present a treatment option for women with oligo/amenorrhoea, hyperandrogenism and PCOS as an adjunct or alternative treatment to pharmaceuticals with a high degree of acceptability by women with PCOS [6]. Preliminary evidence for equivalent treatment effects were found for the two pharmaceuticals and three herbal medicines. These were bromocriptine, in the management of hyperprolactinaemia andVitex agnus-castus and clomiphene for infertility and ovulation induction and Cimicifuga racemosa and Tribulus terrestris. Herbal medicine had positive adjunct effects with the pharmaceuticals Spirinolactone in the management of hyperandrogenism (Glycyrrhiza Spp.), and clomiphene for PCOS related infertility (Cimicifuga racemosa). It is important however to highlight that evidence was provided by a limited number of clinical studies, some with significant risks for bias; particularly Tribulus terrestris, Glycyrrhiza glabra alone and in combination with Paeonia lactiflora and Paeonia lactiflora in combination with Cinnamomum cassia.

May mga kababaihan na hindi naman nababagay sa oral contraceptive pills na may magkasamang estrogen at progestin. Ang alternatibong reseta ng doktor dito ay progesterone (tulad ng Provera).  Ito ay iniinom sa sampu hanggang labing-apat na araw kada isa hanggang tatlong buwan. Nakakatulong ito para magkaregla ang babae para maiwasan ang kanser sa lining ng matres (endometrial cancer) pero walang epekto ito sa taghiyawat at sobrang buhok. Puwede ring mabuntis kung ito ang iniinom na gamot.
Many women with PCOS have decreased sensitivity to insulin, the hormone that regulates glucose (sugar) in the blood. This condition, known as insulin resistance, is a major risk factor for type 2 diabetes. Women with PCOS often have type 2 diabetes, which occurs more frequently in women with PCOS. Signs of insulin resistance include weight gain (especially around the waist), acanthosis nigricans (skin thickening around the neck, armpits, belly, button, and other creases), and skin tags.

In patients with polycystic ovarian syndrome (PCOS) who are obese, endocrine-metabolic parameters markedly improve after 4-12 weeks of dietary restriction. Their sex hormone–binding globulin (SHBG) levels rise, and free testosterone levels fall by 2-fold. [66] Serum insulin and insulin-like growth factor-1 (IGF-1) levels also decrease. In patients with PCOS who are obese, weight loss is associated with a reduction of hirsutism and a return of ovulatory cycles in 30% of women, thereby improving pregnancy rates, as well as improving glucose tolerance and lipid levels. [12, 3]
Obesity is associated with PCOS. Obesity not only compounds the problem of insulin resistance and type 2 diabetes (see below), but also imparts cardiovascular risks. PCOS and obesity are associated with a higher risk of developing metabolic syndrome , a group of symptoms, including high blood pressure, that increase the chances of developing cardiovascular disease. It has also been shown that levels of C-reactive protein (CRP), a biochemical marker that can predict the risk of developing cardiovascular disease, are elevated in women with PCOS. Reducing the medical risks from PCOS-associated obesity is important.
When the former NFL cheerleader Natalie Nirchi stopped menstruating at age 17, she was diagnosed with polycystic ovary syndrome (PCOS), a hormone disorder affecting up to 10 percent of women of reproductive age. She didn’t initially show any of the physical symptoms, like excess hair growth, cystic acne, or obesity, but a blood test revealed that she had high levels of testosterone and an ultrasound showed cysts on her ovaries.
According to Dr. Geoffrey Redmond, an endocrinologist specializing in female hormones, “Just because the ovaries are not functioning as much doesn’t mean the other abnormalities won’t still be present.” He goes on to point out that studies show male hormone levels climb fairly sharply with age.2 This could mean a worsening of symptoms such as excess hair growth as those hormones become more active. It could also mean insulin-related issues such as diabetes and cardiovascular health could become more problematic.
She vain, but she's vain about her aesthetic, not her body. She mentions her imperfections all the time rather than hiding them; she knows she has cellulite, we know that she has cellulite, it isn't something she's trying to hide from the world. Her imperfections are part of her 'poor and free' aesthetic (see gutterpunks for an example of a subculture that glorifies this). The people who point out the problems with her body are adding nothing to the discussion. The comments about her body flaws do nothing but clutter the threads with self-serving, childish garbage, usually in horrible tumblr-speak. Like yeah, we get that Luna's breasts are saggy. We've seen them and heard it a billion times already. Just stop.

Jump up ^ Dewailly D, Andersen CY, Balen A, Broekmans F, Dilaver N, Fanchin R, Griesinger G, Kelsey TW, La Marca A, Lambalk C, Mason H, Nelson SM, Visser JA, Wallace WH, Anderson RA (2014). "The physiology and clinical utility of anti-Mullerian hormone in women". Human Reproduction Update (Review). 20 (3): 370–85. doi:10.1093/humupd/dmt062. PMID 24430863.
In addition to improving reproductive and metabolic factors, the reduction in body weight may be associated with reduced incidence of complications during pregnancy and the neonatal period. In this context, lifestyle change should be the first choice for weight loss because medications to reduce weight could have side effects and bariatric surgery may be associated with preterm and small for gestational age births 14.
Diagnosis of polycystic ovarian syndrome (PCOS) is relatively straightforward. Common criteria established by the Rotterdam Conference in 2003 include at least two of three characteristics (oligomenorrhea, clinical and/or biochemical hyperandrogenism and ultrasound criteria) in the absence of other disease. PCOS is the most common hormonal disorder in women worldwide with prevalence estimates between 4%-8% but as high as 25% in some populations[1]. Women often initiate medical care for a cluster of PCOS symptoms (infertility, hirsutism and irregular menstrual cycles) that ultimately are not the most concerning medical consequences of PCOS [diabetes mellitus (DM), coronary artery disease (CAD), endometrial hyperplasia/cancer]. Here exists an important paradigm in the recognition and treatment of PCOS.

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