Dok goodevening po may pcos po ako pinainum po ako dati ng ob kp ng metformin at clomid saka folic acid po posible po ba kaya na mabuntia na po akO. At ok lang po ba pasabayin ko ung gamot na po un? 6Months ko na po kaso di nakakausap ob ko kasi po nandito ako sa saudi dinala po ako ng asawa ko dito para po sakali makabuo na kamo salamat po sana po masagot nyo po question ko. Godbless
yeah, the constant nitpicking about things she can't help is annoying. people are desperate for milk so they'll try to make a topic out of everything. for example, that anon who was saying how gross her arm looks because it has stretch marks and loose skin. what's she supposed to do about that? shes a shitty person but i gaurentee none of the anons on this thread are perfect or even attractive enough to be such nitpickers
Removing or slowing the growth of excess hair.  Shaving, bleaching, plucking, waxing, and applying over-the-counter hair-removal creams are effective, albeit temporarily methods to get rid of unwanted excess hair. For more permanent results, you might try laser hair removal or electrolysis but these are expensive, require repeated treatments, and are not guaranteed to be successful.

A su hija la han diagnosticado una afección llamada síndrome del ovario poliquístico ("PCOS", por sus siglas en inglés). El PCOS es un desequilibrio hormonal. Afecta los ovarios. Estos son los órganos que guardan los óvulos de la mujer. El PCOS posiblemente también altere el resto del cuerpo. Si se deja sin tratar, el PCOS puede ocasionar graves problemas de salud. El tratamiento no puede curar el problema, pero sí ayuda a reducir los síntomas y a evitar trastornos de salud.
Medical therapy inhibits hair growth without eliminating hair already present. Therefore, medical therapy usually is combined with mechanical methods of hair removal, such as electrolysis or lasers. Electrolysis refers to the insertion of an electrode to destroy individual hair follicles. It is ideal for removing small areas of sparse hair of any color. Laser hair removal is a common, safe and effective cosmetic procedure that also is performed for removal of unwanted facial and body hair. Laser therapy is more expensive than electrolysis but is faster, less painful, and requires fewer sessions. Laser therapy destroys hair by targeting the pigment (melanin) in the hair follicle and is ideally suited for dark-haired, light-skinned individuals. Longer-wavelength lasers with cooling devices can be used for individuals who have red, true blond, or white hair and for dark-skinned people. With appropriate therapy, there is up to a 70% reduction in hair density in treated areas, with remaining hairs becoming thinner in diameter within 3-6 months of treatment. Most patients then require some degree of maintenance treatment, usually every 6-12 months.
Obesity that occurs with PCOS needs to be treated because it can cause numerous additional medical problems. The management of obesity in PCOS is similar to the management of obesity in general. Weight loss can help reduce or prevent many of the complications associated with PCOS, including type 2 diabetes and heart disease. Consultation with a dietician on a frequent basis is helpful until just the right individualized program is established for each woman.
Niveles elevados de insulina. La insulina es una hormona que contribuye en el procesamiento de los alimentos hasta convertirlos en energía. La resistencia a la insulina se da cuando las células corporales no responden normalmente a la insulina. Como consecuencia, los niveles de insulina en sangre están más elevados de lo normal. Muchas mujeres con SOP tienen resistencia a la insulina, en especial aquellas con sobrepeso y obesidad, que tienen hábitos alimenticios poco saludables, no realizan suficiente actividad física o tienen antecedentes familiares de diabetes (por lo general, diabetes tipo 2). Con el paso del tiempo, la resistencia a la insulina puede desencadenar diabetes tipo 2.
I don't mean to break any hearts, but if something happens to Lurch, the chances of Tuna fixing herself are still near zero. She's addicted to the life, they fight plenty and she has made mention before of hooking customers up, etc. It's very rare for a junkie couple to have one person lifting all the weight. On the off chance he does go away, she'll latch on to someone else and get back into the same role (holding / palming / whatever)

High cholesterol and triglyceride levels increase the risk of cardiovascular disease. Getting your cholesterol and triglyceride levels in an optimal range will help protect your heart and blood vessels. Cholesterol management may include lifestyle interventions (diet and exercise) as well as medications to get your total cholesterol, LDL, HDL, and triglycerides in an optimal range.
I've noticed a repeating pattern with cows where someone makes an off hand comment about their appearance, which was probably more of a: "wow that looks fucking bizarre but I don't want to be flat out rude but am so baffled I still have to comment" comment. Which I assume is what happened with the angel shit. If anyone actually said that. She just misinterpreted it as a compliment.
my experiences of being arrested for heroin were in manhattan and nassau county, not the bronx but I'm sure it's the same out there. there are so many heroin arrests & arrests in general in metro NY. possession just isn't important, especially since Lurch doesn't have any open cases besides that one. they would never take something like that to trial.

Research shows over and over again that managing your weight, even shedding a small percentage of your excess pounds (ie, abdominal fat) and exercising regularly can improve symptoms such as irregular periods and infertility, and improve the effectiveness of medications used to help manage your glucose and improve insulin resistance in polycystic ovary syndrome (PCOS).
PCOS is a multifaceted syndrome that affects multiple organ systems with significant metabolic and reproductive manifestations. Treatment should be individualized based on the patient's presentation and desire for pregnancy (Figure 219,29–35). Devices and medications used to treat manifestations of PCOS, and their associated adverse effects, are described in Table 2.19,29–33,36
Diagnosis of polycystic ovarian syndrome (PCOS) is relatively straightforward. Common criteria established by the Rotterdam Conference in 2003 include at least two of three characteristics (oligomenorrhea, clinical and/or biochemical hyperandrogenism and ultrasound criteria) in the absence of other disease. PCOS is the most common hormonal disorder in women worldwide with prevalence estimates between 4%-8% but as high as 25% in some populations[1]. Women often initiate medical care for a cluster of PCOS symptoms (infertility, hirsutism and irregular menstrual cycles) that ultimately are not the most concerning medical consequences of PCOS [diabetes mellitus (DM), coronary artery disease (CAD), endometrial hyperplasia/cancer]. Here exists an important paradigm in the recognition and treatment of PCOS.
We undertook two searches of the scientific literature. The first search sought pre-clinical studies which explained the reproductive endocrine effects of whole herbal extracts in oligo/amenorrhoea, hyperandrogenism and PCOS. Herbal medicines from the first search informed key words for the second search. The second search sought clinical studies, which corroborated laboratory findings. Subjects included women with PCOS, menstrual irregularities and hyperandrogenism.

Lifestyle interventions are usually required for long term sustainable results. PCOS women who smoke have higher free androgen levels and IR as measured by HOMA-IR, QUICKI and the insulin sensitivity index following 75 g OGTT[104]. Thus PCOS women who smoke have an additional reason to stop smoking. In more general population studies (non-PCOS) comprised mostly of middle-aged women, lifestyle intervention is more effective than metformin in preventing the progression to DM. Dietary and exercise intervention decreased the 4 year progression to DM in patients at risk (non-diabetic, elevated fasting and/or OGTT glucose) by almost 50%[105]. Realizing the limitations of applying this population sample to young PCOS women, it still highlights the benefit of non-pharmacological treatment. PCOS women randomized to both metformin and lifestyle interventions (compared to placebo) showed improvements in HOMAIR after 4 mo[106]. In European adolescents with PCOS who failed to achieve improvements in HOMA-IR after 6 mo of lifestyle intervention, both metformin and placebo reduced IR over 6 mo, although metformin offered no benefit over placebo[107]. Lifestyle modification in adolescents has been successful in reducing hyperandrogenism[103]. Modest weight loss of about 5% bodyweight has also been shown to lower hyperandrogenism[108] which may ultimately improve IR.
What you're talking about actually exists - it's called loperamide or Imodium, a widespread drug that exerts an effect only on the mu opioid receptors in the myenteric plexus. It cannot cross the blood-brain barrier. On the other hand, if you want an analgesic, you will have to cross the blood-brain barrier. With cannabinoles, you have different affinities and activities acting on different systems, while for an opioid analgesic the same process that gives the addictive rush. From a purely neurochemical perspective, the difference is that for cannabinoids, the addictive-euphoric and the pain-relieving effects take place on different receptors and it's possible to isolate cannabinoids that have no or little psychoactive effects while for opioids, the effect that gives pain relief is exactly the same as that responsible for addiction. Some opioids have a relatively slow absorption or they can be packaged as an extended release pill that keeps it from hitting the opioid receptors hard and fast. This will prevent it from having the addictive rush that causes compulsive redosing and addiction. But any systemically administered opioid that kills pain will also be at least a little addictive and euphoric. Hope that helps.
This website is written and published by the research team at Insulite Health, an authority on PCOS for over a decade.The information on the Insulite Health website has not been evaluated by the FDA. Products mentioned are not intended to treat, diagnose, cure or prevent any disease. Individual results may vary. The information and products are not intended as a substitute for the advice or medical care of a qualified health care professional. Insulite Health urges you to seek the advice of your health care professional before undertaking any dietary or lifestyle changes and to share with your provider any information pertaining to your well-being, including the advantages and risks of using of supplemental nutrition products.
Our search identified 33 laboratory (pre-clinical) studies (Figure 1). Eighteen studies met the inclusion criteria, nine reported on receptor binding assays or ovarian or pituitary (brain) cell cultures, [36–44] and nine used an animal experimental model with hormone assays and/or post-mortem examination of ovarian, uterine and brain histology, [45–53] (Table 1). We excluded 15 studies for the following reasons; investigation of effects in male animals (n = 4) and investigations which commenced with constituents that were isolated from herbal medicines (n = 5). Six studies were excluded due to no clinical evidence found (n = 6).
Lifestyle measures to achieve a weight loss of 5%-10% in overweight women can help regulate ovulation and periods. Although the basic approach of nutrition is needed, it can be more challenging to lose weight and maintain weight loss with PCOS. Dr. Dunaif from Northwestern is very encouraging that even “a little bit of weight reduction and exercise can improve insulin sensitivity.”
Various laparoscopic methods, including electrocautery, laser drilling, and multiple biopsy, have been used with the goal of creating focal areas of damage in the ovarian cortex and stroma. According to the Society of Obstetricians and Gynaecologists of Canada (SOGC), laparoscopic ovarian drilling may be considered in women with clomiphene-resistant PCOS, especially in the presence of other laparoscopic indications. [2] A small French study also suggested that surgical management via ovarian drilling with hydrolaparoscopy may be beneficial in cases of PCOS that are resistant to clomiphene citrate. [87]
Studies have attempted for years to show an advantage to metformin for ovulation induction and as an adjunct to more advanced fertility treatments. In ovulatory PCOS women metformin was associated with improved serum and follicular fluid AMH levels as well as insulin values; these changes were not seen in anovulatory PCOS women[71]. Despite the demonstration of negative effects of IR on reproductive outcome, the vast majority of evidence does not show improvement in live birth rates when metformin is used strictly for fertility[72], although treatment does improve ovulatory status[72,73].
Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects about 5 to 10 percent of women during their childbearing years. Typically, the ovaries contain multiple small cysts, which are often slightly enlarged. About 1 in 5 women have polycystic ovaries appearing on ultrasound scans but do not have the other features of this syndrome. These cysts do not require surgical removal. Polycystic ovaries make more male hormones (androgens) than do normal ovaries. The exact cause for PCOS is not known, but sometimes it is hereditary.
Although metformin is associated with better clinical pregnancy rates (positive beta hCG) (pooled OR 2.31; 95% CI: 1.52 to 3.51; 8 trials; 707 women), there is no evidence of better live birth rates (the main variable used to evaluate the effectiveness of a treatment for infertility) when this drug is used alone (pooled OR 1.80, 95% CI: 0.52 to 6.16; 3 trials; 115 women) or in combination with CC (pooled OR 1.16; 95% CI: 0.85 to 1.56; 7 trials; 907 women) 36. From a reproduction standpoint, there is also no benefit for its use in short (less than four weeks) or long (more than four weeks) periods prior to starting CC treatment in women with PCOS. Therefore, the use of metformin should be restricted to the treatment of glucose intolerance or type 2 diabetes in women with PCOS and should not be used to induce ovulation 9,36.
“We are seeing an explosion in polycystic ovary syndrome in adolescent girls, and I think it’s due to the fact that we are also seeing an explosion in obesity in adolescent girls,” Nestler said. “It’s quite possible that if those girls had remained a healthy weight, that they would still carry the genes that predispose them, but they wouldn’t be expressing the disorder.”
PCOS es un complemento que ayuda a equilibrar los niveles hormonales (exceso de testosterona) en las mujeres con SOP. Esos desequilibrios hormonales provocan en la mayoría de los casos signos externos de hiperandrogenismo como exceso de vello, caída excesiva del cabello y acné. Al regular tus niveles hormonales, conseguirás suavizar y mejorar esos signos externos 🙂
Herbal medicine may present a treatment option for women with oligo/amenorrhoea, hyperandrogenism and PCOS as an adjunct or alternative treatment to pharmaceuticals with a high degree of acceptability by women with PCOS [6]. Preliminary evidence for equivalent treatment effects were found for the two pharmaceuticals and three herbal medicines. These were bromocriptine, in the management of hyperprolactinaemia andVitex agnus-castus and clomiphene for infertility and ovulation induction and Cimicifuga racemosa and Tribulus terrestris. Herbal medicine had positive adjunct effects with the pharmaceuticals Spirinolactone in the management of hyperandrogenism (Glycyrrhiza Spp.), and clomiphene for PCOS related infertility (Cimicifuga racemosa). It is important however to highlight that evidence was provided by a limited number of clinical studies, some with significant risks for bias; particularly Tribulus terrestris, Glycyrrhiza glabra alone and in combination with Paeonia lactiflora and Paeonia lactiflora in combination with Cinnamomum cassia.
I've noticed a repeating pattern with cows where someone makes an off hand comment about their appearance, which was probably more of a: "wow that looks fucking bizarre but I don't want to be flat out rude but am so baffled I still have to comment" comment. Which I assume is what happened with the angel shit. If anyone actually said that. She just misinterpreted it as a compliment.
For those women that after weight loss still are anovulatory or for anovulatory lean women, then the ovulation-inducing medications clomiphene citrate[74] and FSH are the principal treatments used to promote ovulation.[medical citation needed] Previously, the anti-diabetes medication metformin was recommended treatment for anovulation, but it appears less effective than clomiphene.[medical citation needed][90]
Other tests that may be helpful but are not necessary for diagnosis include measurement of LH and follicle-stimulating hormone (FSH) levels to determine a serum ratio of LH/FSH. A ratio greater than 2 generally indicates PCOS, but there are no exact cutoff values because many different assays are used.26 The FSH level is more helpful in ruling out ovarian failure.26
Although there isn’t a single cure for PCOS, lifestyle and nutritional changes can significantly improve the hormonal imbalances that are so prevalent in PCOS. Weight loss and exercise will reduce the levels of insulin and targeted nutritional supplements can help balance out the systemic biochemistry. A healthy lifestyle is the best medicine and through a comprehensive and consistent improvement in diet and activity, PCOS symptoms can be effectively managed or diminished, and some can be made to disappear completely.
In the case of Polycystic Ovarian Syndrome, excess insulin causes the ovaries to produce excess testosterone, which can prevent ovulation and result in infertility. High insulin levels can also increase the conversion of testosterone into estrogen, which affects weight gain and the formation of ovarian cysts.5 Excess glucose is stored in fat cells that continue to pump out excess estrogen, further destabilizing the hormone system. In the vascular system, insulin increases the risk of heart disease and it is a known precursor to diabetes.6 Unfortunately, these risks increase as a woman ages.
there is no "trial" lmao. you would have flown out for nothing. it's a two minute thing, TOPS. he probably got appointed a public defender today. or maybe not even appointed one, just applied to be appointed one. the first or second time they just ask you to bring in paperwork proving you're poor and need a public defender. when you do get one, the lawyer just keeps adjourning it, like six or more times usually. then you're asked to get into a program or a detox or whatever. at the end he might get probation. each court appearance is less than 5 minutes long.
Pioglitazone (Actos®) and Rosiglitazone (Avandia®) are insulin-sensitizing agents that improve glucose tolerance and insulin resistance. These drugs are approved by the Food and Drug Administration (FDA) for the treatment of diabetes. Although they are not approved for treatment of PCOS, they have been shown to be effective for this purpose in many studies.

On March 1, 2012, the US Food and Drug Administration (FDA) updated health care professionals regarding changes to the prescribing information concerning interactions between protease inhibitors (drugs for management of human immunodeficiency virus [HIV] and hepatitis B infection) and certain statin drugs. The combination of these drugs may raise the blood levels of statins and increase the risk for myopathy. Rhabdomyolysis, the most serious form of myopathy, can cause kidney damage and lead to kidney failure, which is life threatening. [62]
Metformin. Metformin is often used to treat type 2 diabetes and may help some women with PCOS symptoms. It is not approved by the FDA to treat PCOS symptoms. Metformin improves insulin's ability to lower your blood sugar and can lower both insulin and androgen levels. After a few months of use, metformin may help restart ovulation, but it usually has little effect on acne and extra hair on the face or body. Recent research shows that metformin may have other positive effects, including lowering body mass and improving cholesterol levels.
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