i wonder if luna's dad knows about how much she complains about him. all he would have to do is google her name to see how much she hates him. if i were her dad and i saw the shit she says about me, i'd kick her to the curb. poor dude is letting her have what she wants, when she wants it, and she STILL talks about him like he's a monster. maybe he's a piece of shit but damn, at least he's trying. what an ungrateful brat

When a woman is not menstruating or ovulating, an insufficient amount of the hormone progesterone is produced. This hormonal imbalance can lead to an overgrowth of the lining of the uterus (endometrial hyperplasia) and can increase a woman's risk of developing endometrial cancer. Women with PCOS who do ovulate and become pregnant tend to have an increased risk of complications such as miscarriage.
A malfunction of the body's blood sugar control system (insulin system) is frequent in women with PCOS, who often have insulin resistance and elevated blood insulin levels. Researchers believe that these abnormalities may be related to the development of PCOS. It is also known that the ovaries of women with PCOS produce excess amounts of male hormones known as androgens. This excessive production of male hormones may be a result of or related to the abnormalities in insulin production.

Many doctors prescribe the drug metformin to help regulate the amount of glucose in the blood. The medication is traditionally used to treat Type 2 diabetes, as it makes the body more sensitive to insulin, and decreases the amount of glucose the liver releases. A meta-analysis published online in June in the journal Human Reproductive Update demonstrated that when metformin is combined with lifestyle modifications such as diet and exercise, it has been shown to help women with PCOS lose more body fat, achieve lower blood sugar, and improve menstruation better than lifestyle modification alone.
There is no cure yet, but there are many ways you can decrease or eliminate PCOS symptoms and feel better. Your doctor may offer different medicines that can treat symptoms such as irregular periods, acne, excess hair, and elevated blood sugar. Fertility treatments are available to help women get pregnant. Losing as little as 5% excess weight can help women ovulate more regularly and lessen other PCOS symptoms. The ideal way to do this is through nutrition and exercise.

This thread fucks me up. I feel so much pity and sadness for this poor girl. Sort of hits close to home, when I turned 18 I moved in with a boy and got really sick and hooked on drugs for 2 years. I left him and got better, never did I ever get as bad as Luna but it could have happened had I been complacent like she is. I hope she finds the courage to leave. I think there's still beauty and potential underneath all the grime and illness, I even like her art sometimes and wish she'd spend more time on her paintings instead of on drugs. Lurch should be in prison for destroying this poor girl before she even had a chance. Sage for blog post.(USER HAS BEEN PUT OUT TO PASTURE)

Some have tried to utilize ultrasound to detect IR. Of note, normoglycemic women often have the phenotypic criteria for polycystic ovaries on ultrasound[54], consistent with other data in young adolescents showing that polycystic ovaries by ultrasound appearance often does not correlate with either anovulatory menstrual cycles or metabolic abnormalities[55]. Therefore ultrasound is too non-specific to use with any reliability in measuring IR.


Polycystic ovary syndrome (PCOS) is not a simple pathophysiologic process for which one treatment addresses all manifestations. It is a condition that occurs in approximately 5 to 10 percent of women of childbearing age.1 It can affect women in many different ways; therefore, physicians must individualize treatment goals and target treatment to specific manifestations. Comorbidities (e.g., cardiovascular risk factors, endocrinologic disease) and the patient's desire for pregnancy must be considered when choosing a treatment regimen.
No evidence that therapeutic agents additional to V. agnus-castus in Mastodynon® affect prolactin concentration. Four withdrew for unknown reasons. All pregnant women were withdrawn from the study. 4 women had miscarriages, all in the active arm. After 2 years there were 21 more pregnancies with 2 miscarriages – evenly spread over active and placebo groups. Women with infertility were included in this study however data from women who conceived were excluded. This may have led to an underestimation of treatment effect (type 1 error).
Along with the hormonal imbalance and insulin resistance, Medling says that chronic, low-grade inflammation is the third player in the syndrome. (5) Follow an anti-inflammatory diet, which includes nutrient and fiber-rich produce that are low on the glycemic index (like apples and berries), grass-fed meats, organic poultry, as well as sources of omega-3s (like chia seeds and fatty fish) and avoids inflammatory, heavily processed foods, like french fries, potato chips, cake, and cookies. You’ll also want to keep track of foods that bother you (like if dairy gives you gas) and avoid those to help you feel better, she says. (6)

If he was using heroin very heavily, that may well be his starting methadone dose (or close to it.) Methadone has a long half life while heroin has a short one, so avoiding withdrawals can take a lot of methadone, initially. Methadone clinics aren't going to leave someone on a high dose though. They'll titrate up until withdrawal subsides, then taper down over time. I'm guessing he started at the clinic around when he got busted, so it's sus af to me that he'd still be taking 130mg. Or that he ever was. Maybe 100. Possibly.


101. Uras R, Orrù M, Pani F, Marotto MF, Pilloni M, Guerriero S, Etzi R, Zedda P, Sorge R, Lello S, et al. Endocrinological, metabolic and clinical features of treatment with oral contraceptive formulation containing ethinylestradiol plus chlormadinone acetate in nonobese women with polycystic ovary syndrome. Contraception. 2010;82:131–138. [PubMed]

Ano nga ba ang PCOS? Ito ay isang hormonal disorder kung saan nagkakaroon ang babae ng mga maliliit na cyst sa kanyang obaryo. Naglalaman ang mga cyst na ito ng mga immature egg cells na hindi kayang mag-trigger ng proseso ng obulasyon. Ibig sabihin, bababa ang lebel ng female hormones tulad ng estrogen at progesterone, at tataas ang lebel ng male hormones katulad ng androgen. Ang imbalance na ito ay magdadala ng iba’t ibang sintomas at epekto sa katawan.
Palm jaggery o palm asukal ay itinuturing na isang malusog na pagpipilian kaysa sa regular na puting asukal dahil sa pagmamay-ari nito upang kontrolin insulin at asukal sa dugo antas. Ito rin ay nagtataglay ng isang mababang glycemic index at magpapalaki enerhiya na antas. Ang mas mataas na mga antas ng insulin ay karaniwan sa mga PCOS pasyente, at ito hindi nilinis uri ng jaggery (o asukal) ay maaaring makabuluhang epekto sa iyong kalusugan kapag isinama sa iyong diyeta.
Medications to cause ovulation. Medications can help the ovaries to release eggs normally. These medications also have certain risks. They can increase the chance for a multiple birth (twins or more). And they can cause ovarian hyperstimulation. This is when the ovaries release too many hormones. It can cause symptoms such as abdominal bloating and pelvic pain.
One time when I was in a&e this junkie was having withdrawals and literally shitting and puking everywhere. The stench was unreal to the point they had to move other patients out of the area, as it was making people sick. The nurses were fucking pissed off and disgusted, of course they couldn't say anything in front of him, but they were bitching about it when they came into my room. The world is not there to entertain and 'ooh' and 'aww' over your projectile shit, Tuna. Stop being a disgusting adult baby.
Mid luteal (day 20) serum progesterone concentration before and after; treatment arm 2.46 (±0.70) to 9.69 (±6.34), p < 0.001. Placebo 1.99 (±0.65) to 2.34 (±0.59) p = 0.08. No description of the distribution of drop-outs or missing data. This suggests the potential imbalance between intervention and control and a possible over-exaggeration for treatment effect.
Además de los medicamentos, hacer ejercicio regularmente y llevar una dieta sana pueden ayudar a controlar el PCOS. Aunque el PCOS dificulta mucho la pérdida del peso, adelgazar aunque sea un poco puede ayudar a reducir algunos de sus síntomas. Hable con el proveedor de atención médica de su hija para obtener más información sobre el adelgazamiento y el PCOS.
Pwedeng magrekomenda ang doktor ng mga lifestyle changes bilang PCOS treatment. Kasama dito ang pag-ehersisyo, para sa kahit maliit na pagbawas sa timbang. Ang kawalan ng kahit limang porsyento ng ating timbang ay makakatulong na sa pagbuti ng ating kondisyon. Bilang ehersisyo, tingnan ang pagtakbo, pagbisikleta, paglangoy, o ang mga simpleng routine na kinabibilangan ng mga push-up, crunches, stretching exercises, at iba pa.
This is an important distinction; given her longtime love for drugs, tendency to abuse everything she gets, and unwillingness to go sober even when she's not on H, there's a good chance that Luna has 'polysubstance dependence' and is chasing the feeling of being 'not sober' by abusing her meds. The drugs she abuses don't have to get her high if that is the case, just do enough to make her feel a change in her consciousness (e.g. sedation, calm). It's common in people with untreated mental illness. Luna probably hates herself so much that she just can't handle being left alone with her sober self.

Cushing's syndrome, sometimes referred to as hypercortisolism, is a hormonal disorder caused by prolonged exposure to high levels of the hormone cortisol. Symptoms may include obesity, thinning arms and legs, a rounded face, and increased fat around the neck. Some causes of Cushing's syndrome is from taking glucocorticoid hormones such as prednisone for inflammatory diseases. Treatment for Cushing's syndrome depends on the cause.
This was originally developed as a blood pressure medication and diuretic for hormonal forms of high blood pressure (hypertension) and fluid retention. “Turns out, in high doses, it’s very good at blocking male hormones,” explains Dunaif. For that reason, it’s used to target excess hair growth, a symptom of PCOS that can be particularly embarrassing.
If a woman's weight is excessive, the physician should be aggressive in championing a weight-loss program. Medications effective for weight loss (in addition to lifestyle modifications) that have been specifically studied in women with PCOS include metformin, acarbose, sibutramine, and orlistat (Xenical). Metformin is probably the first-line medication for obesity or weight reduction in patients with PCOS. Metformin results in a decrease in body mass index (BMI) of 1 to 2 kg per m2 or weight loss up to 6 lb, 10 oz to 8 lb, 13 oz (3 to 4 kg)10,46,49; acarbose results in an approximate 3 kg per m2 decrease in BMI24; sibutramine results in a decrease in BMI of 5.8 kg per m2 and weight loss of 31 lb, 11 oz (14.4 kg)26; and orlistat results in weight loss of approximately 11 lb (5 kg).50 However, a recent systematic review suggested that metformin is not effective for lowering BMI in patients with PCOS.1

Clinically speaking, the hyperandrogenism seen in PCOS is associated with hirsutism more than acne or alopecia and therefore hirsutism is an impetus for young women seeking care[2]. Many PCOS women are also overweight (BMI > 25kg/m2) or obese (BMI > 30kg/m2), although adiposity is not a defining criteria for PCOS. Obesity is highly prevalent in the general population and in PCOS women and is an independent risk factor for CAD[3]. Obesity in adolescents is correlated with insulin resistance (IR) and dyslipidemia[4]. PCOS related ovulatory dysfunction in adolescents often correlates to adolescent obesity[5]. Genetic predisposition to PCOS has been suspected for many years[6] and data link obesity and metabolic disturbances in PCOS with genetic polymorphisms[7,8]. Even male first degree relatives of women with PCOS have a higher incidence of metabolic syndrome (MS), the closest corollary to PCOS in men[9].

Chaste berry (Vitex agnus-castus): This herb has been used for centuries for hormone imbalances and is considered an adaptogen. Chaste berry is one of the most common herbs used to treat PCOS because it helps to stimulate and stabilize the function of the pituitary gland. The pituitary gland is responsible for the release of luteinising hormone which can reduce the level of estrogen and androgen levels while raising progesterone levels.
Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects about 5 to 10 percent of women during their childbearing years. Typically, the ovaries contain multiple small cysts, which are often slightly enlarged. About 1 in 5 women have polycystic ovaries appearing on ultrasound scans but do not have the other features of this syndrome. These cysts do not require surgical removal. Polycystic ovaries make more male hormones (androgens) than do normal ovaries. The exact cause for PCOS is not known, but sometimes it is hereditary.

Many doctors prescribe the drug metformin to help regulate the amount of glucose in the blood. The medication is traditionally used to treat Type 2 diabetes, as it makes the body more sensitive to insulin, and decreases the amount of glucose the liver releases. A meta-analysis published online in June in the journal Human Reproductive Update demonstrated that when metformin is combined with lifestyle modifications such as diet and exercise, it has been shown to help women with PCOS lose more body fat, achieve lower blood sugar, and improve menstruation better than lifestyle modification alone.

Combination birth control pills — those with estrogen and Prometrium (progesterone) — are frequently prescribed to women with PCOS not looking to get pregnant. If the main concern is irregular periods and the resulting potential health risks, this is a great option. “Birth control pills are very good for protecting the lining of the uterus in women who are chronically anovulatory,” says Dunaif.
When the syndrome was first described in 1935 by American gynecologists Irving Stein, and Michael Leventhal, it was considered a rare disorder. Today as many as five million women in the United States may be affected, according to the Department of Health and Human Services, but researchers are still just beginning to uncover the disorder’s full impact.

Side effects: Red clover has been associated with headaches, nausea, vaginal bleeding, muscle ache and rash. Do not take this herb if you have conditions that are worsened by estrogen exposure such as endometriosis, breast cancer, ovarian cancer or if you are pregnant or breastfeeding. Red clover might also increase the chance of bleeding so avoid this herb if you have any kind of bleeding disorder.

Where PCOS is associated with overweight or obesity, successful weight loss is the most effective method of restoring normal ovulation/menstruation, but many women find it very difficult to achieve and sustain significant weight loss. A scientific review in 2013 found similar decreases in weight and body composition and improvements in pregnancy rate, menstrual regularity, ovulation, hyperandrogenism, insulin resistance, lipids, and quality of life to occur with weight loss independent of diet composition.[73] Still, a low GI diet, in which a significant part of total carbohydrates are obtained from fruit, vegetables, and whole-grain sources, has resulted in greater menstrual regularity than a macronutrient-matched healthy diet.[73]
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