Although metformin is associated with better clinical pregnancy rates (positive beta hCG) (pooled OR 2.31; 95% CI: 1.52 to 3.51; 8 trials; 707 women), there is no evidence of better live birth rates (the main variable used to evaluate the effectiveness of a treatment for infertility) when this drug is used alone (pooled OR 1.80, 95% CI: 0.52 to 6.16; 3 trials; 115 women) or in combination with CC (pooled OR 1.16; 95% CI: 0.85 to 1.56; 7 trials; 907 women) 36. From a reproduction standpoint, there is also no benefit for its use in short (less than four weeks) or long (more than four weeks) periods prior to starting CC treatment in women with PCOS. Therefore, the use of metformin should be restricted to the treatment of glucose intolerance or type 2 diabetes in women with PCOS and should not be used to induce ovulation 9,36.
the last time luna deleted her blog, before she remade the one she has now, i googled her name because i couldn't find her blog and i wanted to see if she had another one, her lolcow page was like the 3rd result and i read every single thread within a few days. so, lolcow may only be the first google results to people who use lolcow BECAUSE they use lolcow, but for me, someone who had never even heard of the site before, it was still one of the first results. people who google her name never visiting lolcow before will still see these threads.
Patients with PCOS who are infertile but desire pregnancy should be referred to a reproductive endocrinologist for further evaluation and management of infertility. Morbidly obese women with PCOS should also be referred for pregnancy risk [2] ; metabolic surgery may be considered in morbidly obese women with PCOS, because many features of this syndrome are reversible with successful weight loss. In vitro fertilization (IVF) is reserved for women with PCOS and unsuccessful gonadotropin therapy or those with other indications for this procedure. [2]
A su hija la han diagnosticado una afección llamada síndrome del ovario poliquístico ("PCOS", por sus siglas en inglés). El PCOS es un desequilibrio hormonal. Afecta los ovarios. Estos son los órganos que guardan los óvulos de la mujer. El PCOS posiblemente también altere el resto del cuerpo. Si se deja sin tratar, el PCOS puede ocasionar graves problemas de salud. El tratamiento no puede curar el problema, pero sí ayuda a reducir los síntomas y a evitar trastornos de salud.
Diagnosis can generally be accomplished with a careful history, physical examination, and basic laboratory testing, without the need for ultrasonography or other imaging. Hyperandrogenism can be diagnosed clinically by the presence of excessive acne, androgenic alopecia, or hirsutism (terminal hair in a male-pattern distribution); or chemically, by elevated serum levels of total, bioavailable, or free testosterone or dehydroepiandrosterone sulfate.23 Measurement of androgen levels is helpful in the rare occasion that an androgen-secreting tumor is suspected (e.g., when a patient has marked virilization or rapid onset of symptoms associated with PCOS).
Hi dok matagal na ako gusto mag ka anak na pressure na ako sa family ko nag aantay ng baby ko 🙁 posible po bang may PCOS aq dahil ang regla q po ay irregular qng hindi po 2months minsan 4months.. nag pa check up na po ako ultrasound at nag pa inject ng anti cervical cancer ang pina painom lang sa ako Metformin tinigil ko na kc wala pa rin nangyare at hindi na din ako bumalik sa ob ko dahil laki na ng gastos ko.. anu pa ba dapat ko try inomin. salamat dok

Dok. Magandang tanghali po. May PCOS din po ako. 19 years old po ako nung nalaman kong may sakit akong Polycystic. Nagkaroon po ako ng kalive in nun dati aman po e okay yung regla ko tas nung nagsasama na kami nung bf ko hndi na ko nagkakameron akala namin buntis ako 1year akong hndi niregla nun. Hiwalay na kami ng ka live in ko ngayon . Niresetahan ako ng doktor ko ng Provera 5 days kong iinumin tas magtake din daw ako ng althea pills pag nagkaregla na. Okay aman sya nagkakaregla naman na ako. Kaso lang pahinto hinto yung pag inom ko kasi mejjo mahal yung pills . At dahil nga pahinto hinto yung pag inom ko ng pills hndi na din ako nagkakamens . Kaya nagtatake ulit ako ng provera.
Medicamentos sensibilizantes de la insulina. Se usan para tratar la diabetes y es frecuente que también se usen para tratar el PCOS. Ayudan al cuerpo a responder a la insulina. A las mujeres que tienen el PCOS pueden ayudarles a reducir los niveles de andrógenos y mejorar la ovulación. Restablecer la ovulación ayuda a que los periodos menstruales sean más más regulares y predecibles.
Moghetti P, Castello R, Negri C, et al. Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation. J Clin Endocrinol Metab. 2000 Jan. 85(1):139-46. [Medline]. [Full Text].
Complementary medicine (CM) use by women has increased during the past ten years [7–11] with rates of use ranging between 26% and 91% [8, 9]. One of the popular types of CM is herbal medicine [11, 12]. Herbal medicines are known to contain pharmacologically active constituents with physiological effects on female endocrinology and have been positively associated with reduced incidences of breast cancer, osteoporosis and cardiovascular disease [13–18].
Polycystic ovary syndrome (PCOS) is not a simple pathophysiologic process for which one treatment addresses all manifestations. It is a condition that occurs in approximately 5 to 10 percent of women of childbearing age.1 It can affect women in many different ways; therefore, physicians must individualize treatment goals and target treatment to specific manifestations. Comorbidities (e.g., cardiovascular risk factors, endocrinologic disease) and the patient's desire for pregnancy must be considered when choosing a treatment regimen.
Píldoras anticonceptivas orales. Contienen una combinación de hormonas femeninas. Estas pastillas pueden ayudar a normalizar el equilibrio de las hormonas y reducir o eliminar los síntomas. Esto reduce el riesgo de cáncer de endometrio para cuando la joven sea mayor. (No es necesario que una adolescente mantenga relaciones sexuales activas para tomar anticonceptivos orales).
I reckon probably the latter though, people do actually want to help her, to the extent that people get pissed off as fuck if you express any of that sort of sentiment in here because we've heard it so often. I imagine a lot of posters view her like PT but worse - it's just frustrating to watch someone ruin their life so spectacularly and reject all the things that would actually make their life better.

Polycystic ovary syndrome is a condition present in approximately 5 to 10 percent of women of childbearing age. Diagnosis can be difficult because the signs and symptoms can be subtle and varied. These may include hirsutism, infertility, menstrual irregularities, and biochemical abnormalities, most notably insulin resistance. Treatment should target specific manifestations and individualized patient goals. When choosing a treatment regimen, physicians must take into account comorbidities and the patient's desire for pregnancy. Lifestyle modifications should be used in addition to medical treatments for optimal results. Few agents have been approved by the U.S. Food and Drug Administration specifically for use in polycystic ovary syndrome, and several agents are contraindicated in pregnancy. Insulin-sensitizing agents are indicated for most women with polycystic ovary syndrome because they have positive effects on insulin resistance, menstrual irregularities, anovulation, hirsutism, and obesity. Metformin has the most data supporting its effectiveness. Rosiglitazone and pioglitazone are also effective for ameliorating hirsutism and insulin resistance. Metformin and clomiphene, alone or in combination, are first-line agents for ovulation induction. Insulin-sensitizing agents, oral contraceptives, spironolactone, and topical eflornithine can be used in patients with hirsutism.
Reglan Active ingredient: metoclopramide $0.37 for pill Reglan is used for short-term treatment of gastroesophageal reflux disease (GERD) in certain patients who do not respond to other therapy. It is used to treat symptoms of a certain digestive problem in diabetic patients (diabetic gastroparesis). Prilosec Active ingredient: omeprazole $0.49 for pill Prilosec relieves symptoms of gastroesophageal reflux disease decreasing the amount of acid in the stomach.

Fasting methods to measure IR have been advocated for many years as an adjunct to DM screening. Elevated fasting insulin levels greater than 20 μU/mL may alone indicate IR. Fasting glucose/insulin ratio (G/I) has also gained some clinical traction. A ratio < 4.5 has in general been shown to be > 90% sensitive in some populations[45] but has never been validated with clamp studies[48]. Some ethnic variation in G/I cutoff ratios may exist[49]. There has been some suggestion that G/I < 7 in very young girls may predict IR[50,51].
Insulin-sensitizing agents, including metformin,31 acarbose (Precose),24 and rosiglitazone (Avandia),20 may be used to treat hirsutism in women with PCOS. Spironolactone22 and rosiglitazone32 have been shown to be more effective than metformin, based on Ferriman-Gallwey hirsutism scores. A Cochrane review suggested that metformin is as effective as oral contraceptives for treating hirsutism in women with PCOS,33 but in contrast, a recent systematic review suggested that metformin is not effective.1 Topical eflornithine cream is FDA-approved for management of unwanted facial hair, but there are no published data regarding its use specifically in women with PCOS. Sibutramine (Meridia), which is approved for obesity management, can also improve hirsutism.26
“My doctor mentioned that one day I might have trouble getting pregnant, but didn’t offer any other information about the disorder,” Nirichi said. Other than the absence of her period, PCOS did not significantly impact her life until college, when she began experiencing shooting pains in her pelvis, mood swings, and rapid weight gain despite a rigorous exercise routine.
This work attempts to give a review of ovarian innervation, the mechanism of regulation of nerve activity and the role of the sympathetic activity in ovarian pathologies affecting reproductive function. We provide a succinct outline of the findings of our group in this area. The participation of stress as an etiological factor for ovarian pathologies throughout animal models and preliminary data in patients with polycystic ovary syndrome give strong support for a participation of sympathetic nerves in the ovary function both in normal and pathological states.
Oral contraceptives (birth control pills) contain a combination of hormones (estrogen and progesterone). Used properly, oral contraceptives can ensure that women with PCOS menstruate every four weeks. This, in turn, lowers the risk of endometrial cancer, which is higher in women with PCOS because they do not menstruate regularly and properly shed the endometrial lining.
Chromium is an essential mineral that helps the body regulate insulin and blood sugar levels. Some research suggests that chromium supplements can help people with diabetes lower their blood glucose levels. One study examined the role of the mineral in women with PCOS. The results indicated that 200 mcg daily of chromium picolinate significantly reduced fasting blood sugar and insulin levels in subjects — enough that the effects were comparable to the pharmaceutical, metformin. While metformin was also associated with lower levels of testosterone, taking a daily dose of 200 mcg of chromium picolinate could help regulate blood sugar levels.
Los medicamentos pueden ayudar a regular su ciclo menstrual y reducir el crecimiento anormal del cabello y el acné. Las píldoras anticonceptivas (para las mujeres que no intentan tener un bebé) y la metformina son dos medicamentos recetados que a menudo son útiles. Si usted tiene diabetes o presión arterial alta, esas afecciones también necesitan tratamiento. Si quiere tener un bebé, existen medicamentos que pueden ayudarla a quedar embarazada.
For once the shirt she's wearing looks clean.Maybe she's lucid enough to get some washing done although thats a far fetched theory. Also, I've tried following Luna on instagram to keep up with milk using two different accounts and she has declined both requests. With one being my art account I assumed that wouldn't look too sus. Is she very picky when it comes to who she lets follow her?
Sperm capacitation must be evaluated to perform the low-complexity treatment (semen evaluation after preparation to estimate the number of sperm with progressive motility, which includes those that theoretically have the ability to ascend the female reproductive tract in vivo and fertilize the egg in the fallopian tube). Thus, the semen is centrifuged and the concentration of capacitated sperm recovered is measured as follows: >10 million recovered motile sperms (any infertility treatment is viable); >5 million (IUI, in vitro fertilization (IVF) or intra-cytoplasmic sperm injection (ICSI) may be performed); between 1 and 5 million (IVF or ICSI may be performed); and <1 million (only ICSI can be performed) 27,28. It is worth noting that if the patient presents with bilateral tubal occlusion in the initial assessment, sperm capacitation is only performed to evaluate the possibility of performing IVF or ICSI 8.

Clomid Active ingredient: clomiphene $0.44 for pill Clomid is a fertility drug, used to stimulate FSH and LH production and hereby the ovaries to produce eggs in ovarian disorders. Metformin Active ingredient: metformin $0.26 for pill Metformin is a biguanide anti-diabetic that works by decreasing the amount of sugar that the liver produces and the intestines absorb.

>>411167 Tuna if she got sent this: "someone drew me and my mans. my heart is truly filled with love. Currently eating ice cream the snails sadly got into, just eating around the slime lol. Matthew's leg is healing and just fell asleep cuddling the snails, he cried when I let them go and said he truly loved my big heart. heading to my evil dads lol wish me luck. at least I can try out my new lipstick for the trainride. Eating the non-slime ice cream until I fall into a peaceful sleep. just trying my best <3"

Angela Grassi, a registered dietitian who also has PCOS, says that because women who are overweight are likely to experience more insulin resistance than those who are not, they can get locked into a cycle of weight gain. “The more weight you gain, the more corresponding insulin your body produces, and the more you continue to gain weight,” she said.
OGTT with 75-g glucose and hourly glucose and insulin measurements has been compared to clamp techniques. Insulin sensitivity calculated by mathematical transformation of measurements has shown good correlation with glucose disposal using clamp techniques[48]. Although the OGTT is easy to perform, these calculations are more complex and make this particular calculation less desirable for clinical use. However these data show that 1 and 2 h levels are often needed to diagnose IR and stress the potential for false negative results with fasting measurements alone. In patients undergoing clamp and OGTT no correlation was observed between fasting glucose/insulin ratios and IR on the clamp[48].
The cysts (fluid filled sacs) in the ovaries can be identified with imaging technology. (However, as noted above, women without PCOS can have many cysts as well.) Ultrasound , which passes sound waves through the body to create a picture of the kidneys, is used most often to look for cysts in the ovaries. Ultrasound imaging employs no injected dyes or radiation and is safe for all patients including pregnant women. It can also detect cysts in the kidneys of a fetus. Because women without PCOS can have ovarian cysts , and because ovarian cysts are not part of the definition of PCOS, ultrasound is not routinely ordered to diagnose PCOS. The diagnosis is usually a clinical one based on the patient's history, physical examination, and laboratory testing.

To be quite precise (Gastroenterofag here): opioids do slow the metabolism and make you crave sugary crap. Weight gain versus loss depends on whether the dose is high enough to actually be too fucked up most of the day to eat (that's why virtually all thin heroin users who go on methadone or subutex end up ballooning: they're no longer taking astronomical doses of opioids that make them too zonked out to eat, as the cross tolerance allows us to give them about 40% less of the equianalgesic dose). Sage for medfagging.

Vitamin D deficiency may play some role in the development of the metabolic syndrome, so treatment of any such deficiency is indicated.[74][75] However, a systematic review of 2015 found no evidence that vitamin D supplementation reduced or mitigated metabolic and hormonal dysregulations in PCOS.[76] As of 2012, interventions using dietary supplements to correct metabolic deficiencies in people with PCOS had been tested in small, uncontrolled and nonrandomized clinical trials; the resulting data is insufficient to recommend their use.[77]