PCOS is the most common cause of anovulatory (pronounced an-OV-yuh-luh-tawr-ee) infertility, meaning that the infertility results from the absence of ovulation, the process that releases a mature egg from the ovary every month. Many women don't find out that they have PCOS until they have trouble getting pregnant...Read more about PCOS NIH - National Institute of Child Health and Human Development
Given the conditions associated with PCOS, the Endocrine Society, the Androgen Excess and PCOS Society, and the American College of Obstetricians and Gynecologists recommend that clinicians evaluate patients' blood pressure at every visit and lipid levels at the time of diagnosis, and screen for type 2 diabetes with a two-hour oral glucose tolerance test regardless of a patient's body mass index. Patients should have repeat diabetes screening every three to five years, or more often if other indications for screening are present.19–21 The Endocrine Society further recommends depression screening, as well as screening for symptoms of obstructive sleep apnea in overweight and obese patients with PCOS.19 However, routine screening for nonalcoholic fatty liver disease or endometrial cancer (using ultrasonography) is not recommended.19
Glucose tolerance testing (GTT) instead of fasting glucose can increase diagnosis of impaired glucose tolerance and frank diabetes among people with PCOS according to a prospective controlled trial. While fasting glucose levels may remain within normal limits, oral glucose tests revealed that up to 38% of asymptomatic women with PCOS (versus 8.5% in the general population) actually had impaired glucose tolerance, 7.5% of those with frank diabetes according to ADA guidelines.
The differential diagnosis of PCOS is broad and includes both endocrinologic and malignant etiologies. Figure 119 provides an algorithm for the workup of select presentations. For any woman with suspected PCOS, the Endocrine Society recommends excluding pregnancy, thyroid dysfunction, hyperprolactinemia, and nonclassical congenital adrenal hyperplasia.19 Depending on presentation, conditions such as hypothalamic amenorrhea and primary ovarian insufficiency should also be excluded. In women with rapid symptom onset or significant virilization, such as deepening voice or clitoromegaly, an androgen-secreting tumor should be ruled out. Finally, Cushing syndrome or acromegaly should be excluded in patients with physical findings that suggest either condition.19 There is no need to order laboratory testing for these conditions if the patient does not have suggestive physical findings.
Traditionally, women with polycystic ovary syndrome (PCOS) have been treated with therapies aimed at relieving specific PCOS symptoms or health risks. Newer treatments being investigated at the University of Chicago Medicine and elsewhere also aim to address what may be a root cause of PCOS: insulin resistance. Many of these new therapies are designed to lower insulin levels, thus reducing production of testosterone.
I reckon probably the latter though, people do actually want to help her, to the extent that people get pissed off as fuck if you express any of that sort of sentiment in here because we've heard it so often. I imagine a lot of posters view her like PT but worse - it's just frustrating to watch someone ruin their life so spectacularly and reject all the things that would actually make their life better.
Methadone is said to not get people "high," but I beg to differ. It doesn't give any of the euphoria that heroin does, nor the rush, but it definitely has a body high to it. I've never taken a dose of methadone over 30mg (which is a typical maintenance dose, btw) and got so high off that I couldn't walk straight. Mentally I was nearly clear though. Maybe Lurch likes feeling physically retarded and it takes him 130mg to get there? Who knows.
Hi dok bru . kailan ko LNG po nalaman na may pcos ako ng mag patingin ako sa doctor 3 buwan po kase akong di dinatnan tas nag kasakit po kase ako dun ko LNG po napag pasyahan na mag patingin sa ob gyn na ultrasound po ako at lumabas po sa resulta ng ultrasound ko na may pcos ako . binigyan po ako ng pampa regla 10 days ko po ininom hanggang sa mag ka roon na ako at nung datnan na po ako almost 2weeks po akong meron tas bumalik po ako sa ob gyn as doctor na pinag konsultahan ko kse nga po almost 2weeks po akong may period then binigyan po ako ng pampatigil after ko pong mainom young gamot nag stop na po ang mens ko. At sabe po ng doctor ko bumalik ako pag tumigil na ang period ko pero di na po ako naka balik para sa next na check up ko sabe po reresetahan ako ng gamot for 6 months na gamutan pero di pa po ako naka balik for follow check up ngayun jan. 12 2016 ko po nalaman na may pcos ako . 20 year old pa LNG ako. Ano po ba mang yayari kung hanggang ngayun di po ako nag pupunta sa ob ko . ano po ang maipapayo nyo saken. Ellaine
Complementary medicine (CM) use by women has increased during the past ten years [7–11] with rates of use ranging between 26% and 91% [8, 9]. One of the popular types of CM is herbal medicine [11, 12]. Herbal medicines are known to contain pharmacologically active constituents with physiological effects on female endocrinology and have been positively associated with reduced incidences of breast cancer, osteoporosis and cardiovascular disease [13–18].
Clinical equivalence for prolactin lowering effects of Vitex agnus-castus (Agnucaston® 40 mg per day) and the pharmaceutical Bromocriptine (Parlodel® 5 mg per day) was found in one study including 40 women with hyperprolactinaemia . Mean concentrations for prolactin following three months treatment with Vitex agnus-castus was significantly reduced from 946 mIU/l (±173) to 529 mIU/l (±297) (p < 0.001). Comparatively, mean prolactin concentration in the Bromocriptine group was significantly reduced from 885 mIU/l (±178) to 473 mIU/l (±266) (p < 0.001) demonstrating that both treatments were effective treatment for women with hyperprolactinaemia (normal reference range 25-628 mIU/l). The mean difference in prolactin reduction of the two groups was not significant (p = 0.96) (Table 2).
Fasting methods to measure IR have been advocated for many years as an adjunct to DM screening. Elevated fasting insulin levels greater than 20 μU/mL may alone indicate IR. Fasting glucose/insulin ratio (G/I) has also gained some clinical traction. A ratio < 4.5 has in general been shown to be > 90% sensitive in some populations but has never been validated with clamp studies. Some ethnic variation in G/I cutoff ratios may exist. There has been some suggestion that G/I < 7 in very young girls may predict IR[50,51].
Metformin. Metformin is often used to treat type 2 diabetes and may help some women with PCOS symptoms. It is not approved by the FDA to treat PCOS symptoms. Metformin improves insulin's ability to lower your blood sugar and can lower both insulin and androgen levels. After a few months of use, metformin may help restart ovulation, but it usually has little effect on acne and extra hair on the face or body. Recent research shows that metformin may have other positive effects, including lowering body mass and improving cholesterol levels.